Blood serum is a blood plasma lacking fibrinogen . Serum is obtained either by natural coagulation of plasma (native serum), or by precipitation of fibrinogen with calcium ions. Most antibodies are retained in sera, and due to the absence of fibrinogen, stability is sharply increased.
Serum is isolated during a blood test for infectious diseases, when evaluating the effectiveness of vaccination ( antibody titer ), as well as in a biochemical blood test.
Immune serum (antiserum) - blood serum containing antibodies against certain antigens . They are administered to the patient for medicinal purposes or as a temporary protection (to create passive immunity) from various diseases [1] . Immune sera are used as medications for many infectious diseases ( tetanus , diphtheria , flu ) and poisoning (snake venoms, botulinum toxin ). A blood serum treatment method ( serotherapy ) was developed at the end of the 19th century by Emil Adolf von Bering , Kitasato Sibasaburo , Emil Roux and Alexander Yersen .
Serums labeled with enzymes , radionuclides and phosphors are used in the diagnosis of certain diseases and in scientific research.
See also
- Serology
Notes
Literature
- Concise Medical Dictionary / Martin, Elizabeth A. .. - 7th. - Oxford, England: Oxford University Press , 2007 .-- ISBN 0-19-280697-1 . .
- Wang, Wendy; Srivastava, Sudhir (2002), "Serological Markers", in Breslow, Lester, Encyclopedia of Public Health , vol. 4, New York, New York: Macmillan Reference USA, pp. 1088-1090