Stefan Schuster ( German: Stefan Schuster ; born November 7, 1961, Meissen ) - German biophysicist , one of the leading experts in the field of organization of metabolism and mathematical modeling in biology , professor of bioinformatics at the Friedrich Schiller University in Jena .
| Stefan Schuster | |
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| Stefan schuster | |
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| Date of Birth | November 7, 1961 (57 years old) |
| Place of Birth | Meissen , Germany |
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| Scientific field | Biophysics , Theoretical Biology , Analysis of metabolic fluxes |
| Place of work | Friedrich Schiller University of Jena |
| Alma mater | Humboldt University of Berlin |
Short biography
Stefan Schuster - a graduate of the Humboldt University in Berlin , in the same department of theoretical biophysics under the leadership of Reinhart Heinrich, he defended his thesis on "Theoretical studies of the relationship between the temporal hierarchy and the principles of optimization of enzymatic reactions." Since 2003 - Professor of the Department of Bioinformatics at the Friedrich Schiller University in Jena. He is the editor of BioSystems magazine, published by Elsevier .
Scientific achievements
Stefan Schuster's area of interest includes bioinformatics and systems theory, including evolutionary game theory [1] , the theory of metabolic control [2] , biological oscillations [3], and analysis of metabolic pathways [4] .
The methods developed by Stefan Schuster in the field of the theory of metabolic control and analysis of metabolic fluxes allowed, inter alia, to predict the viability of bacterial mutants [5] , calculate the metabolic rate of coenzymes [6] , determine the level of production of antibiotics [7] , and evaluate the possibility of carbohydrate synthesis from fats in humans and higher animals through detours of metabolism [8] . Stefan Schuster is also involved in the development of computer programs for analyzing metabolic pathways [9] . As of May 2019, his work was cited more than 14,500 times, the Hirsch index is 49 .
Notes
- ↑ Thomas Pfeiffer, Stefan Schuster. Game-theoretical approaches to studying the evolution of biochemical systems (Eng.) // Trends in Biochemical Sciences. - 2005-1. - Vol. 30 , iss. 1 . - P. 20-25 . - DOI : 10.1016 / j.tibs.2004.11.006 .
- ↑ Stefan Schuster. Control Analysis in Terms of Generalized Variables Characterizing Metabolic Systems (Eng.) // Journal of Theoretical Biology. - 1996-10. - Vol. 182 , iss. 3 - P. 259–268 . - DOI : 10.1006 / jtbi.1996.0163 .
- ↑ Stefan Schuster, Marko Marhl, Thomas Höfer. Modeling of simple and complex responses to intercellular signaling (English) // European Journal of Biochemistry. - 2002-03-01. - Vol. 269 , iss. 5 - P. 1333–1355 . - DOI : 10.1046 / j.0014-2956.2001.02720.x .
- ↑ Stefan Schuster, Luis F. de Figueiredo, Anja Schroeter, Christoph Kaleta. Combining Metabolic Pathway Analysis with Evolutionary Game Theory. Explaining the occurrence of a low-yield pathways by an analytic optimization approach (Eng.) // Biosystems. - 2011-8. - Vol. 105 , iss. 2 - P. 147–153 . - DOI : 10.1016 / j.biosystems.2011.05.057 .
- ↑ Jörg Stelling, Steffen Klamt, Katja Bettenbrock, Stefan Schuster, Ernst Dieter Gilles. Metabolic network structure of regulation and regulation (English) // Nature. - 2002-11. - Vol. 420 , iss. 6912 . - P. 190–193 . - ISSN 1476-4687 0028-0836, 1476-4687 . - DOI : 10.1038 / nature01166 .
- ↑ Luis F. de Figueiredo, Toni I. Gossmann, Mathias Ziegler, Stefan Schuster. Pathway analysis of NAD + metabolism (English) // Biochemical Journal. - 2011-10-15. - Vol. 439 , iss. 2 - P. 341-348 . - ISSN 1470-8728 0264-6021, 1470-8728 . - DOI : 10.1042 / BJ20110320 .
- ↑ Maria TE Prauße, Sascha Schäuble, Reinhard Guthke, Stefan Schuster. Computing the various pathways of penicillin synthesis and their molar yields (Eng.) // Biotechnology and Bioengineering. - 2016-1. - Vol. 113 , iss. 1 . - P. 173–181 . - DOI : 10.1002 / bit.25694 .
- ↑ Luis F. de Figueiredo, Stefan Schuster, Christoph Kaleta, David A. Fell. Can sugars be produced from fatty acids? A test case for pathway analysis tools (English) // Bioinformatics. - 2008-11-15. - Vol. 24 , iss. 22 - P. 2615-2621 . - ISSN 1367-4803 1460-2059, 1367-4803 . - DOI : 10.1093 / bioinformatics / btn500 .
- ↑ A. v. Kamp, S. Schuster. Metatool 5.0: fast and flexible elementary modes analysis (English) // Bioinformatics. - 2006-08-01. - Vol. 22 , iss. 15 - P. 1930-1931 . - ISSN 1460-2059 1367-4803, 1460-2059 . - DOI : 10.1093 / bioinformatics / btl267 .