Perfluorodecalin (octadecafluorodekalin) is a cyclic perfluorinated alkane , a derivative of decalin , in which all hydrogen atoms are replaced by fluorine atoms.
| Perfluorodecalin | |
|---|---|
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| Are common | |
| Systematic name | Octadecafluorodecalin |
| Abbreviations | PFD |
| Traditional names | Perfluorodecalin |
| Chem. formula | C 10 F 18 |
| Physical properties | |
| condition | liquid |
| Molar mass | 462.081 g / mol |
| Density | 1,917 g / cm³ |
| Thermal properties | |
| T. melt. | -6.7 ° C |
| T. Kip. | +142 ° C |
| Chemical properties | |
| Water solubility | 10 ppm |
| Classification | |
| Reg. CAS number | 306-94-5 |
| Pubchem | |
| Reg. EINECS number | |
| SMILES | |
| Inchi | |
| Reg. EC number | 206-192-4 |
| RTECS | |
| CHEBI | |
| Chemspider | |
| Security | |
| Toxicity | non toxic |
Content
Properties
Perfluorodecalin is a colorless liquid, insoluble in water, alcohol, non-polar and polar solvents. Well dissolves gases. Chemically inert, resistant to 400 ° C.
Cis-trans isomerism
Perfluorodecaline exists in cis and trans stereoisomeric forms that differ in the mutual arrangement of the cycles. Both isomers are biologically and chemically inert and have very similar properties. The most noticeable difference lies in the melting point: for cis-isomer, it is −3.6 ° C; for trans-isomer - +18 ° C; for a mixture of 50/50 - −6.7 ° C.
Getting
In industry, perfluorodecalin is obtained by fluorination of tetralin or decalin with cobalt (III) fluoride in the Fowler process .
Application
Due to the high solubility of oxygen, perfluorodecalin has wide application in medicine. It is used as a component of blood substitutes, such as, for example, Perftoran , a domestic blood- replacement drug.