Tatyana Nikolaevna Shekhovtsova (born August 7, 1947 , Sharya , Kostroma region, USSR ) - Russian chemical analyst, doctor of chemical sciences , professor , deputy head of the department of analytical chemistry at the Faculty of Chemistry, MV Lomonosov Moscow State University, head of the kinetic laboratory analysis methods.
| Tatyana Nikolaevna Shekhovtsova | |
|---|---|
| Date of Birth | August 7, 1947 (71 year) |
| Place of Birth | Sharya , USSR |
| A country |  USSR →  Russia |
| Scientific field | analytical chemistry |
| Place of work | |
| Alma mater | |
| Academic degree | Doctor of Chemical Sciences |
| Academic title | |
Content
Family
Tatyana Nikolaevna was born in Sharya, Kostroma region, in 1947. Father is a military historian, graduated from the Leningrad State Pedagogical Institute. Herzen and the M. Frunze Military Academy , the mother, having graduated from the same institute, also received a pedagogical education, during the war she taught chemistry and biology at school.
Husband - Shpigun Oleg Alekseevich , doctor of chemical sciences, professor, corresponding member. RAS; The family has two sons.
Study
She graduated with a gold medal from an English special school, where, along with the usual subjects, English and American literature was taught, as well as history and geography in English. In 1965 she entered the Faculty of Chemistry of the Moscow State University named after MV Lomonosov . From the second year I seriously began to do research under the guidance of Associate Professor I. F. Dolmanova in the laboratory of kinetic methods of analysis of the Department of Analytical Chemistry. As a student, she participated in international student conferences on analytical chemistry. In 1975 she graduated from the Faculty of Chemistry with honors.
Tatiana Nikolaevna took an active part in public life of the school, faculty and university: at school she was secretary of the Komsomol organization, in her student years she was elected to the committee committee of the Komsomol faculty, university, was secretary of the Komsomol organization of the chemistry faculty, a member of the party committee of the faculty.
Research and teaching
After graduating from the faculty, she was left to work at the Department of Analytical Chemistry as a junior research assistant, in the following years she went from an assistant department to a professor.
Since her student years she has been engaged in research in the field of kinetic methods of analysis, in 1974 she defended her thesis in analytical chemistry on the topic "The use of activators in kinetic methods for the determination of chromium."
In 1996 she defended her doctoral thesis on the topic “Enzymatic methods of analysis: determination of effector hydrolases and oxidoreductases” [1] .
Since the beginning of the 1980s, T. N. Shekhovtsova led a new direction in the development of kinetic methods — the use of reactions catalyzed by enzymes in them, that is, enzymatic methods of analysis. Since then, her research interests have included the creation of scientific foundations and the practical application of enzymatic methods; identifying and studying the mechanism of action of effectors (inhibitors and activators) of enzymes of various classes [2] ; development of methods for immobilization of enzymes; creation of methods for the determination of biologically active substances - effectors, substrates, cofactors of enzymes; development of test methods and test devices based on immobilized enzymes for the determination of toxicants in various objects. She identified inorganic and organic inhibitors and activators of a number of enzymes of the classes of oxidoreductases and hydrolases (peroxidases, alcohol dehydrogenases, alkaline and acid phosphatases, pyrophosphatases, etc.) isolated from various sources; studied the mechanism of their action [3] . The proposed physical and chemical methods of immobilization of these enzymes on carriers of various types (silica gels, polyurethane foams, etc.). Based on native and immobilized enzymes, unique in terms of sensitivity, selectivity, simplicity and expressivity of the technique (including visual test techniques) of a number of highly toxic substances (mercury, lead, cadmium, organo-mercury compounds, phenols, etc.) have been developed in environmental objects, biological fluids, food products [4] [5] [6] [7] [8] .
In May 1999 she received the title of professor, became deputy head of the department for educational and methodical work.
Since 2005, Tatyana Nikolaevna is the head of the laboratory of kinetic methods of analysis and heads a group of enzymatic methods of analysis. Currently, under her leadership, staff, graduate students and students of the laboratory deal with the problems of creating and applying in practice chemical analysis of biocatalytic optical (spectrophotometric, fluorescent, Raman) sensory systems based on natural biopolymers - enzymes, proteins, polysaccharides, for the rapid, sensitive and selective determination a wide range of quality markers for pharmaceuticals, cosmetics, food and petroleum products, markers of various diseases in biological objects in order to predict and diagnose socially significant diseases. TN Shekhovtsova is the author and co-author of more than 250 publications, participates in numerous Russian and international scientific conferences devoted to the problems of the development of biochemical methods of analysis, devoted to the problems of the development of biochemical methods of analysis and analytical chemistry in general. She was a member of the organizing committees of some of them.
In addition to scientific work, Tatiana Nikolaevna is actively engaged in teaching activities: since 1975 she has been teaching classes for students of chemical and biological faculties, since 2000 she has been giving lectures on the general course of analytical chemistry for students of chemical faculty and the faculty of fundamental physical and chemical engineering; fundamental medicine; He is the author and lecturer of the special course on kinetic, biochemical and biological methods of analysis. Co-author of all editions of the textbook "Fundamentals of Analytical Chemistry" [9] , written by members of the Department of Analytical Chemistry, Moscow State University, co-author of numerous methodological and practical manuals on analytical chemistry [10] . Under her leadership, defended 20 master's theses and more than 40 theses. She repeatedly traveled to give lectures on kinetic and biochemical methods to universities in the United States, Japan, and Germany.
Currently a member of the academic council of the chemical faculty of Moscow State University.
Awards and membership in academic societies
Since 1995 he has been a member of the Bureau of the Scientific Council on Analytical Chemistry of the Russian Academy of Sciences , Chairman of the NSAH Commission on Teaching Analytical Chemistry, Deputy Chairman of the NSAH Commission on Biochemical Methods.
Laureate of the MV Lomonosov Prize for teaching activities in 2002.
In 2009, Tatiana Nikolaevna was awarded the honorary title “ Distinguished Professor of Moscow State University ”.
Notes
- ↑ Shekhovtsova T. N. Enzymatic methods of analysis: determination of effectors of hydrolases and oxidoreductases. Diss. ... Dr. chemical sciences. Moscow, Moscow State University, 1996
- ↑ Assay of enzyme effectors. Dolmanova IF, Shekhovtsova TN, Kutcheryaeva VV Talanta, 1987, V.34, N 1, P. 201–205.
- ↑ Application of oxidases in analysis. Shekhovtsova TN, Muginova SV, Mizgunova UM, Dolmanova IF Quimica Analytica. 1996. V. 15, N4, P. 312-320
- ↑ Determination of phenols using various peroxidases. Gazaryan IG, Loginov DB, Lialulin AL, Shekhovtsova TN. Analytical Letters, V.27. N.15. P. 2917-2930
- Reac Determination of zinc (II) reactivity of apoenzymes of alkaline phosphatases from diverse sources. Grishina LE, Poskonnaya NA, Shekhovtsova TN Analytical Letters, 2000.V. 33. N 11. P. 2197-2217.
- ↑ Determination of catecholamines in pharmaceutical formulations. Poliakov AE, Muginova SV, Shekhovtsova TN 2011. Current Topics in Analytical Chemistry, V. 8. P. 51-75
- Solid sen----flu sen sen sen sen complex complex Rodionov PV, Veselova IA, Shekhovtsova TN Analytical and Bioanalytical Chemistry, 2014. V. 406. N 5. P. 1531-1540
- Novel A novel multi-purpose enzymatic system and procedures for the selection of flavonoids in herbal pharmaceuticals and plant materials. Veselova I., Malinina L., Barsukova M., Buslova T., Shekhovtsova T. Talanta. 2017. V. 171. P. 108-111
- ↑ Shekhovtsova T.N., Alov N.V., Barbalat Yu.A., Borzenko A.G., Garmash A.V., Dolmanova I.F., Zolotov Yu.A., Karyakin A.A., Morosanova E. I., Pasekova N. A., Pletnev I. V., Proskurnin M. A., Prokhorova G. V., Sergeev N. M., Fadeeva V. I. Basics of Analytical Chemistry. In 2 t. Ed. Zolotova Yu. A. (6th ed., Revised and extra.) M .: IAC Academy, Moscow, 2014. 416 p.
- ↑ Shekhovtsova T.N., Barbalat Yu. A., Garmash A.V., Zolotov Yu.A., Monogarova O.V., Osipova E.A., Oskolok K.V., Pasekova N.A., Prokhorova G. V., Sorokina N. M., Fadeeva V. I., Shapovalova E. N., Shvedene N. V., Shpigun O. A. Basics of Analytical Chemistry: A Practical Guide M .: Laboratory of Knowledge, 2017. 462 p. .