Barry James Marshall ( born Barry James Marshall ; born September 30, 1951 , Kalgoorlie , Western Australia ) - Australian doctor , winner of the Nobel Prize in medicine and physiology in 2005 . Professor of Clinical Microbiology, University of Western Australia . For the first time proved that gastric ulcer in most cases is caused by the bacterium Helicobacter pylori . Commander of the Order of Australia .
| Barry james marshall | |
|---|---|
| English Barry james marshall | |
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| Date of Birth | September 30, 1951 (67 years) |
| Place of Birth | Kalgoorlie , Australia |
| A country | Australia |
| Scientific field | microbiology |
| Place of work | |
| Alma mater | University of Western Australia |
| Academic degree | |
| Awards and prizes |  Nobel Prize in Physiology or Medicine ( 2005 ),  |
| Site | |
Member of the Australian Academy of Sciences (1999) [2] , the Royal Society of London (1999) [3] , foreign member of the National Academy of Sciences of the USA (2008) [4] .
Biography
Barry Marshall was born on September 30, 1951 in the city of Kalgoorlie ( Western Australia ). When he was seven years old, his family moved to Perth . Marshall graduated from the University of Western Australia , where he received a bachelor of medicine and surgery in 1975.
In 1979, Marshall began working at the , where in 1981 he met Robin Warren , who was then a senior pathologist at the hospital and had long been interested in Helicobacter pylori. Together they began research on helical bacteria and their connection with gastritis . In 1982, they isolated the primary culture of Helicobacter pylori in a patient and hypothesized that this bacterium causes ulcers and stomach cancer. However, this assumption was met with ridicule in the medical and scientific communities. Later in 1998, Marshall said: “Everyone was against me, but I knew that I was right” [5] .
After the experiments on the infection of laboratory pigs failed, in 1984 Marshall himself drank a culture of bacteria isolated from the patient, and he soon developed symptoms of gastritis with achlorhydria : gastric discomfort, nausea , vomiting, and a peculiar smell from the mouth ( halitosis ). Then Marshall was able to demonstrate that he was able to heal his helicobacter gastritis with a 14-day course of treatment with bismuth salts and metronidazole. On the 14th day after infection, the biopsy did not show the presence of bacteria in the stomach. This proved, in accordance with Koch’s postulates , that H. pylori causes gastritis. An article describing the experiment was published in the journal [6] and became the most quoted article of the journal [7] .
After that, Marshall worked at the Royal Perth Hospital (1985–86), then at the University of Virginia ( USA ) (1986–1996). Later he returned to the University of Western Australia , where he worked in 1998–2003 [8] . Marshall continues to work at the University’s H.pylori research laboratories in the field of bacterium research [9] .
Awards
In 2005, Barry Marshall and his colleague Robin Warren received the Nobel Prize in Physiology and Medicine "For his work on the effect of Helicobacter pylori bacteria on the onset of gastritis and gastric and duodenal ulcers" [10] .
Other awards [11] :
- 1994 -
- 1995 - Australian Medical Association Award
- 1995 - Albert Lasker Prize for Clinical Medical Research
- 1995 - John Scott Medal
- 1996 - International Gairdner Prize
- 1997 -
- 1998 - Heineken Prize in Medicine
- 1998 -
- 1998 - from the Royal Society
- 1999 - Benjamin Franklin Medal in Natural Sciences
- 2001 -
- 2002 -
- 2003 - Centenary Medal
- 2006 - American Gastroenterological Association [12]
- 2007 - Companion of the Order of Australia ( Companion of the Order of Australia ).
Social activities
In 2016, he signed a letter calling for Greenpeace , the United Nations, and governments around the world to stop the fight against genetically modified organisms ( GMOs ) [13] [14] [15] .
Notes
- ↑ German National Library , Berlin State Library , Bavarian State Library , etc. Record # 139878653 // General Regulatory Control (GND) - 2012—2016.
- ↑ Professor Barry Marshall (eng.)
- ↑ Barry Marshall (English)
- ↑ Barry J. Marshall (English)
- ↑ Barry Marshall Interview, H. Pylori and the Making of Myth (not available link) . Academy of Achievement (May 23, 1998). The appeal date is January 28, 2007. Archived February 26, 2012.
- ↑ Marshall BJ, Armstrong JA, McGechie DB, Glancy RJ Attempt to fulfil Koch's postulates for pyloric Campylobacter (English) // Med. J. Aust. : journal. - 1985. - April ( vol. 142 , no. 8 ). P. 436-439 . - PMID 3982345 .
- ↑ Van Der Weyden, Martin B; Ruth M Armstrong and Ann T Gregory. The 2005 Nobel Prize in Physiology or Medicine (Eng.) // Medical Journal of Australia : journal. - Medical Journal of Australia, 2005. - Vol. 183 , no. 11/12 . - P. 612-614 .
- ↑ Professor Barry Marshall . University of Western Australia (July 28, 2006). The appeal date is January 28, 2007. Archived February 26, 2012.
- ↑ Marshall, Barry Helicobacter pylori Research Laboratory . University of Western Australia (August 26, 2002). The appeal date is January 28, 2007. Archived February 26, 2012. Found there.
- ↑ The Nobel Prize in Physiology or Medicine 2005 . Nobel Foundation (2005). The appeal date is January 28, 2007. Archived August 25, 2011.
- ↑ Curriculum Vitae . Nobel Foundation (2005). The appeal date is January 28, 2007. Archived February 26, 2012.
- ↑ American Gastroenterological Association. William Beaumont Award (unavailable link) (English)
- ↑ 107 Nobel laureates sign letter blasting Greenpeace over GMOs
- ↑ Laureates Letter Supporting Precision Agriculture (GMOs)
- ↑ List of Nobel laureates who signed the letter