Serotonin transporter

Serotonin transporter
Available Structures
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PDB ID List
Identifiers
	, 5-HTT, 5HTT, HTT, OCD1, SERT, SERT1, hSERT, Solute Carrier Family 6 (neurotransmitter transporter), member 4, solute carrier family 6 member 4, 5-HTTLPR
External IDs
Gene ontology
Functions
Cell component
Biological process
	Sources: Amigo / QuickGO
RNA expression profile
Orthologists
	Wikidata
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The serotonin transporter , or the sodium-dependent serotonin transporter, is an intracellular protein that is a product of the SLC6A4 gene ( English solute carrier family 6 member 4 ) and is abbreviated as SERT ( SERotonin Transporter ) or 5-HTT ( 5-HydroxyTriptamine Transporter ). ^[1] Serotonin transporter belongs to the family of monoamine transporter proteins. Its physiological function is the reuptake and transport of serotonin from the synaptic cleft back to the presynaptic neuron that secreted it . ^[2]

Content

Mechanism of Action

Physiological Functions

Pharmacology

Ligands

Genetic variations and polymorphisms

Variations in promoter length

Neuroimaging

A combination of neuroimaging and genetics

Notes

↑ SLC6A4 Gene (Protein Coding) (neopr.) .
↑ SLC6A4 - Sodium-dependent serotonin transporter - Homo sapiens (Human) - SLC6A4 gene & protein (neopr.) .

[1] SLC6A4 Gene (Protein Coding) (neopr.) .

[2] SLC6A4 - Sodium-dependent serotonin transporter - Homo sapiens (Human) - SLC6A4 gene & protein (neopr.) .