Titok Marina Alekseevna (born February 4, 1959, Minsk)
| Marina Alekseevna Titok | |
|---|---|
| Date of Birth | February 4, 1959 (60 years) |
| Place of Birth | Minsk |
| Scientific field | genetics , microbiology |
| Place of work | Faculty of Biology, BSU |
| Alma mater | Belarusian State University in Minsk . |
| Academic degree | doctor of biological sciences |
| Academic title | Professor |
Content
Biography
Marina Alekseevna Titok was born on February 4, 1959 in Minsk.
In 1981 she graduated with honors from the Belarusian State University with a degree in genetics .
Since 1981, she worked as a senior laboratory assistant and junior researcher in the biochemical genetics of bacteria sector at the Research Laboratory of Experimental Biology of the Belarusian State University .
From 1991 she worked as an assistant, then as an assistant professor in the department of genetics, from 2005 - professor in the department of genetics, from 2009 - professor in the department of microbiology of the BSU .
In 1991 she defended her thesis.
In 1997 he was awarded the academic title of associate professor .
The scientific degree of the doctor of biological sciences was awarded in 2005.
The academic title of professor was awarded in 2007.
Pedagogical activity
Marina Alekseevna Titok delivers lectures on the following courses: "Vector systems", "Basics of molecular biology ", "Genetics of microorganisms ", "extrachromosomal genetic structures of bacteria ", "molecular aspects of evolution ". Conducts laboratory and practical classes in the course "Basics of Cell Molecular Biology "
Scientific Activities
His research interests are the study of the molecular genetic organization of the extrachromosomal genetic elements of gram-positive and gram - negative bacteria , including those ensuring the survival of microorganisms in extreme environmental conditions ( antibiotics , xenobiotics ); molecular genetic engineering of strains producing biologically active compounds (solvents, insecticidal toxins, antimicrobial compounds); creation of vector systems for molecular cloning in cells of gram-positive and gram - negative bacteria ; physiological-biochemical and molecular-genetic analysis of bacteria- destructors of oil isolated from extreme natural sources ( Belarus , Libya , Iraq , Antarctica ).
He has 194 scientific and educational works, including 1 monograph , 1 textbook, 122 articles, 3 patents of the Republic of Belarus and 1 copyright certificate for an invention. She prepared 3 candidates of sciences and 9 masters .
M.A. For 9 years Titok has been a member and then deputy chairman of the WAC expert. Currently a member of two Doctoral Theses Defense Councils and two Academic Councils.
Main publications
Educational publications
1. Titok MA, Maximova N.P. Tests on the course "Genetics" for students of the correspondence department methodical recommendations. Minsk, BSU, 1995. 11 p.
2. Maksimova N.P., Titok M.A. Guidelines for registration coursework and thesis on genetics guidelines. Minsk, BSU, 1995. 8 p.
3. Titok M.A. Maksimova N.P., Anokhina V.S. Guidelines for the course "Genetics" guidelines. Minsk, BSU, 1997. 20 p.
4. Glushen S.V., Kunitskaya MP, Titok MA Methodical instructions for practical training in the course "Cytology and Histology" methodical instructions. Minsk, BSU, 1997. p.
5. Titok MA, Grenev V.V. “Chromosome Mapping”, study guide Minsk, BSU, 2003. 12 p.
6. Titok MA, Grenev V.V. “Linked inheritance of traits and crossing over” a teaching aid. Minsk, BSU, 2003. 10 p.
7. Titok MA, Grenev V.V. “Gene Interaction”, Teaching Guide Minsk, BSU, 2003. 20 p.
8. Glushen S.V., Grenev V.V. , Kunitskaya MP, Titok MA "Cytology and histology" guidelines. Minsk, BSU, 2004. 6 p.
9. Titok MA, Anokhin V.S. "Theory of Evolution" guidelines for conducting seminars.
10. Anokhin V.S., Titok M.A. "Theory of Evolution" guidelines for examinations of students of the correspondence department
11. Maksimova N.P., Titok M.A., Anokhina V.S., Khramtsova E.A., Grinev V.V., Kunitskaya MP Collection of tasks in genetics: a manual for students of the Faculty of Biology. - Minsk: BSU. - 2008. - 167 s.
12. Maksimova N.P., Titok M.A., Kunitskaya MP, Khramtsova E.A., Anokhina V.S. Genetics: guidelines for laboratory studies for students of the biological faculty of specialties 1-31 01 01 - Biology, 1-33 01 01 - Bioecology. - Minsk: BSU. - 2008.- 64 p.
13. Titok M.A. Part 1. "Molecular aspects of evolution." Tutorial. 2011. - 183s.
14. Titok M.A. Vector systems Part I. Introduction to the methodology of recombinant DNA. // Guidelines for the course "Vector Systems" Mn: Publishing House of BSU. 2013. 56 p.
Monograph
Titok M.A. PLASMIDES OF GRAMOPOSITIVE BACTERIA / Ed. Yu.K. Fomicheva.– Mn: Publishing House of BSU. - 2004. - 120 p.
Author's Certificate
Titok MA, Maximov N.P., Prokulevich V.A., Fomichev Yu.K. A.S. No. 1599434 USSR. Plasmid DNA pMTF59 proposed for transposon mutagenesis of bacteria of the Enterobacteriaceae family / Declared 06/20/1988. Publ. 10/15/1990. // Discoveries. Inventions. - 1990. - № 38. - p. 111.
Patents
1. A.S. 7537 IPC: C12N15 / 63 Shuttle vector for molecular cloning in bacteria Bacillus subtilis and Escherichia coli (versions) and method of its construction / A.V. Lagodich, M.A. Titok (RB). - № А20030886
2. Shuttle vector for molecular cloning in bacteria of the genus Pseudomonas and Escherichia coli and method for its construction / K.V. Kovalchuk, S.L. Vasilenko, M.A.Titok (RB). - № А20071525
Articles
1. Titok MA, Prokulevich V.A., Maksimova N.P., Fomichev Yu.K. The use of plasmid pM3 Pseudomonas sp. for transposon mutagenesis of Erwinia bacteria // Mol. Genet. Microbiol. Virusol. - 1989. - № 11. - p. 45-48.
2. Titok MA, Lysak V.V., Kulba A.M. R-plasmids of optional methylotrophic Pseudomonas: characterization of the plasmid pM3 // Bulletin of BSU. - Ser. 2, No. 2. - 1989. - p. 42-46.
3. Titok MA, Maksimova NP, Fomichev Yu.K. Characteristic of the RM plasmid pM3 (IncP9) of a wide range of hosts // Mol. Genet. Microbiol. Virusol. - 1991. - № 9. - p. 9-13.
4. Titok MA, Olekhnovich I.N., Evtushenkov A.N. Cloning of the rep region of a wide range of plasmid hosts pM3 (IncP9) // Mol. Genet. Microbiol. Virusol. - 1991. - № 3. - p. 18-23.
5. Greated A., Titok MA, Krasowiak R., Fairclough RJ, Thomas CM The replication and stable-inheritance functions of IncP-9 plasmid pM3 // Microbiol. - 2000. - Vol. 146. - p. 2249-2258. (inaccessible link)
6. Lotareva, OV, Nezametdinova, VZ, Fedorina, E.A., Poluektova, E.U., Titok, MA, Prozorov, A.A. Conjugative mobilization, carried out with a high frequency of natural strains of Bacillus subtilis, carrying a large plasmid // Genetics. - 2001. - V. 37, No. 12. - p. 1598-1603.
7. Lotareva OV, Poluektova E.U., Titok MA, Prozorov A.A. Large plasmid from the soil strain Bacillus subtilis, carrying out conjugative mobilization with high frequency // Reports Acad. Of science - 2001. - V. 379, No. 1. - P. 130-131.
8. Lotareva O.V., Poluektova E.U., Titok M.A., Prozorov A.A. Soil strain of Bacillus subtilis, containing a large plasmid, providing a high frequency of mobilization transfer // Microbiology. - 2002. - T. 71., № 2. - p. 255-257.
9. Krasowiak R., Smalla K., Sokolov S., Kosheleva IA, Sevastianovich YR, Titok MA, Thomas CM PCR primers for detection and characterization of IncP-9 plasmids // FEMS Microbiol. Ecol. - 2002. - Vol. 42, No. 2. - p. 217-225.
10. Titok MA, Chapuis J., Selezneva YV, Lagodich, AV, Prokulevich VA, Ehrlich SD, Janniere L. Bacillus soil isolates: plasmid replicon analysis and construction of the new theta-replicating vector // Plasmid. - 2003. - Vol. 49, No. 1. - p. 53-62.
11. Titok M.A. Use of the plasmid of a wide range of pM3 hosts (IncP-9) for the genetic analysis of bacteria of the family Enterobacteriaceae // Genetics. - 2003. - V. 39, No. 12. - p. 1606-1611.
12. Titok MA, Lagodich A.V. Molecular genetic analysis of the rep-region of the theta-type plasmid pBS72 bacteria Bacillus subtilis // Reports of the National Academy of Sciences of Belarus. - 2003. - T. 47, No. 4. - p. 67-70.
13. Titok MA, Lagodich A.V., Selezneva Yu.V. Plasmid composition of bacteria Bacillus subtilis, isolated from natural sources // Bulletin of BSU. - 2003. - Ser. 2, No. 3. - p. 35-38.
14. Lagodich A.V., Shtanyuk Ya.V., Prozorov A.A., Titok M.A. Characterization of plasmid replication systems of natural strains of Bacillus subtilis // Mol. Biol. - 2004. - V. 38, № 3. - p. 1-5.
15. Titok MA, Lagodich A.V. Characteristic of rep-regions of plasmid Bacillus subtilis // News of the National Academy of Sciences of Belarus. - 2004. - № 2. - p. 61-65.
16. Titok M.A. Genetic determinants of the incompatibility of the plasmid pMT2 (IncP-9) // Bulletin of BSU. - 2005. - Ser. 2, No. 1. - pp. 31-36.
17. Titok M.A. The property of temperature instability of the plasmid pMT2 (IncP-9) // Bulletin of BSU. - 2005. - Ser. 2, No. 1. - p. 26-31.
18. Vasilenko S.L., Titok M.A., Maksimova N.P. Creating a system for the genetic analysis of bacteria Pseudomonas mendocina. // Genetics. - 2000. - V. 36. - № 1.- p.28-34.
19. Vasilenko S.L., Maksimova N.P., Titok M.A. Optimization of mutagenesis conditions for bacteria Pseudomonas mendocina. // Bulletin of BSU. - 2003. - Ser. 2. - № 1. - with. 43-47.
20. Vasilenko S.L., Maksimova N.P., Titok M.A. Conjugation mapping of bacteria Pseudomonas mendocina // Genetics. - 2003, T. 39, No. 11.
21. Vasilenko S.L., Maksimova N.P., Titok M.A. Construction of a genetic map of bacteria Pseudomonas mendocina // Genetics, 2003, T. 39, №12.
22. Levchuk A.A., Vasilenko S.L., Bulyga I.M., Titok M.A. Thomas KM Characteristics of naphthalenutilizing bacteria strains of the genus Pseudomonas // Izvestiya RAN – 2005 .–– №2.– p.162-167.
23. Lagodich A.V., Cherva E.A., Shtanyuk Ya.V., Prokulevich V.A., Fomichev Yu.K., Prozorov A.A. Titok M.A. Creating a vector system for molecular cloning in cells of Bacillus subtilis and Escherichia coli // Mol. Biol. - 2005. - V. 39. – №2. - p.345-348 Short message
24. Titok MA, Prokulevich V.A., Jeannier L. Influence of the replicative complex of the host cell on the inheritance of the plasmid pBS72 Bacillus subtilis // Reports of the National Academy of Sciences of Belarus. 2005. T.49. Number 3. C.70-76.
25. Titok M.A. Functional analysis of the rep region of the plasmid pMT2 (IncP-9) // Reports of the National Academy of Sciences of Belarus. 2005. T.49. №4. P.81-87.
26. Sevastsyanovich, YR, Titok, MA, Krasowiak, R., Bingle, LEH, Thomas, CM (2005). Ability of IncP-9 plasmid pM3 to replicate in Escherichia coli is dependent on both rep and par functions. Mol. Microbiol., 57 (3), 819-833.
27. Titok M., Suski C., Dalmais B., Ehrlich SD, Janniere L. The replicative polymerases of PolC and DnaE are required for the replication of the Bacillus subtilis plasmid pBS72 // Microbiology (2006), 152, 1471–1478. (inaccessible link)
28. Levchuk A.A., Bulyga I.M., Izmalkova T.Yu., Sevastyanovich Ya.R., Kosheleva I.A., Thomas CM, Titok M.A. Nah-plasmids of the IncP-9 group of natural strains of Pseudomonas // Mol.biol. 2006, T.40 No. 5, p. 835–843.
29. Bulyga I.M., Titok M.A. organization of plasmid replication initiation systems of the IncP-9 group // Reports of the National Academy of Sciences of Belarus. 2006. V. 5. №5. P.63-68 .
30. Nezametdinova V.Z., Fedorina E.A., Poluektova E.U., Titok M.A., Prozorov A.A. Conjugation ability and comparative characterization of large plasmids contained in natural Bacillus subtilis strains from different regions of the East European Plain // Microbiology. - 2007. - T.76, № 2. - C. 1-6.
31. Janniere L, Canceill D, Suski C, Kanga S, Dalmais B, Lestini R, Monnier AF, Chapuis J, Bolotin A, Titok M, Le Chatelier E, Ehrlich SD. Genetic evidence for a link between glycolysis and DNA replication. // PLoS ONE. 200716; 2: e447.
32. Vasilenko S. L., Titok M. A. Features of inheritance of biodegradation plasmids in cells of homo- and heterologous hosts. // Microbiology.-2008.-T.77, №1.- p. 16-22.
33. Sevastsyanovich YR, Krasowiak R., Bingle LEH, Haines AS, Sokolov SL, Kosheleva IA, Leuchuk AA, Titok MA, Smalla K., Thomas CM Diversity of IncP-9 plasmids of Pseudomonas // Microbiology.- 2008. - V .154, № 10. - p. 2929-41. (inaccessible link)
34. Al-Shammari F.D.H., Titok M.A. Features of the organization of genes of biodegradation of natural naphthalene utilizing bacteria. // Reports of the National Academy of Sciences of Belarus. - 2011. - t.55, №2. - p.77-81.
35. Sechenikov A.A., Titok M.A. Functional analysis of the rep region of the plasmid pBS267 of the IncP-9 group, determining the degradation of captolactam. // Reports of the National Academy of Sciences of Belarus. - 2011. - t.55, №2. - p.70-75.