REBASE (from the English R estriction E nzyme Data base ) is a database containing information on restriction endonucleases , DNA methyltransferases, and other components of restriction-modification systems [1] . REBASE contains an extensive set of links, recognition and cleavage sites, sequences and structures, as well as information on the commercial availability of each enzyme. REBASE is one of the oldest biological databases; it has its roots in the collection of restrictase enzymes collected by Richard Roberts before 1980 [2] . Since then, the journal Nucleic Acids Research regularly publishes descriptions of this database [3] [4] .
| REBASE | |
|---|---|
 | |
| Content | |
| Description | Database of components of restriction-modification systems |
| Organisms | Mostly prokaryotes |
| Contacts | |
| Laboratory | New england biolabs |
| The authors | Richard Roberts |
| Original publication | PMID 19846593 |
| Date of issue | 01/31/2011 |
| Availability | |
| Site | rebase.neb.com |
| URL to download | ftp.neb.com |
| Other | |
| Release frequency | Monthly |
| Curation | Yes |
See also
- Restriction endonucleases
- DNA methyl transferase
- Restriction Systems-Modifications
Links
- ↑ Roberts RJ , Vincze T. , Posfai J. , Macelis D. REBASE - a database for DNA restriction and modification: enzymes, genes and genomes (Eng.) // Nucleic Acids Res. - 2010 .-- Vol. 38 , no. Database issue . - P. D234 — D236 . - DOI : 10.1093 / nar / gkp874 . - PMID 19846593 .
- ↑ Roberts RJ Restriction and modification enzymes and their recognition sequences (Eng.) // Nucleic Acids Res. - 1980. - Vol. 8 , no. 1 . - P. r63 — r80 . - DOI : 10.1093 / nar / 8.1.197-d . - PMID 6243774 .
- ↑ Roberts RJ Restriction and modification enzymes and their recognition sequences (Eng.) // Nucleic Acids Res. - 1982. - Vol. 10 , no. 5 . - P. r117 — r144 . - DOI : 10.1093 / nar / 10.5.1770 . - PMID 6280143 .
- ↑ Roberts RJ , Macelis D. REBASE - restriction enzymes and methylases (Eng.) // Nucleic Acids Res. - 1993. - Vol. 21 , no. 13 . - P. 3125-3137 . - DOI : 10.1093 / nar / 21.13.3125 . - PMID 8392714 .