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Vomitoxin

Vomitoxin , also deoxynivalenol (abbr. DON) - organic matter , trichothecene mycotoxin , a secondary metabolite produced by several types of micromycetes - microscopic mold fungi of the genus Fusarium ( Fusarium culmorum , Fusarium graminearum ). It is a contaminant . Highly toxic. Causes severe poisoning, accompanied by vomiting (from the English. Vomiting - vomiting ) and gastrointestinal disorders. It has an immunosuppressive effect [1] [2] .

Vomitoxin
Vomitoxin2DCSD.svg
Are common
Systematic
name
(3α, 7α) -3,7,15-trihydroxy-12,13-epoxytrichothec-9-en-8-one
AbbreviationsDON
Traditional namesDeoxynivalenol,
vomitoxin
Chem. formulaC 15 H 20 O 6
Physical properties
conditionsolid crystalline
Molar mass296.3157 ± 0,0152 g / mol
Thermal properties
T. melt.152 ° C
Classification
Reg. CAS number51481-10-8
Pubchem
Reg. EINECS number
SMILES
Inchi
Chemspider
Security
LD 5046 mg / kg (mouse, oral)
Toxicity

Highly toxic immunosuppressant


Hazard TT.svg

Biosynthesis

 
Vomitoxin biosynthesis

Notes

  1. ↑ Gautam, P. and Dill-Macky, R. 2011. Type I host resistance and Trichothecene Accumulation in Fusarium-infected Wheat Heads. American Journal of Agricultural and Animal Sciences 6 (2): 231-241. [one]
  2. Yer Beyer M, Klix MB, Klink H, Verreet JA (2006): tillage, cultivar and triazole fungicides on ox. Journal of Plant Diseases and Protection 113: 241–246. [2]
Source - https://ru.wikipedia.org/w/index.php?title=Vomitoxin&oldid=87002044


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