Phosphoglyceratmutase ( English Phosphoglycerate mutase , PGM ), also phosphoglycerutomutase is an enzyme that catalyzes the reaction of the internal transfer of a phosphate group from C-3 to C-2, converting 3-phosphoglycerate to 2-phosphoglycerate (stage 8 glycolysis ).
| Phosphoglyceratmutase-1 (brain) | |
|---|---|
 | |
| Designations | |
| Characters | PGAM1 ; PGAMA |
| Entrez gene | 5223 |
| Hgnc | 8888 |
| Omim | 172250 |
| Refseq | NM_002629 |
| Uniprot | P18669 |
| Other data | |
| Cipher cf | 5.4.2.11 |
| Locus | 10th hr , 10q25.3 |
| Phosphoglyceratmutase-2 (muscle) | |
|---|---|
| Designations | |
| Characters | PGAM2 |
| Entrez gene | 5224 |
| Hgnc | 8889 |
| Omim | 261670 |
| Refseq | NM_000290 |
| Uniprot | P15259 |
| Other data | |
| Cipher cf | 5.4.2.11 |
| Locus | 7th hr , 7p13 -p12 |
Mechanism of Action
Glycolysis
| 1,3-diphospho- D- glycerate | Phosphoglycerate kinase | 3-phospho- D- glycerate | Phosphoglyceratmutase | 2-phospho- D- glycerate | ||
| ADP | ATP | |||||
| ADP | ATP | |||||
| Phosphoglycerate kinase | Phosphoglyceratmutase | |||||