| # | The Minister | A photo | Leadership period | Academic title | Note |
|---|
| one | Vasily Ivanovich Razumovsky |  | 1919 - 1920 | M.D | |
| 2 | Sergey Nikolaevich Davidenkov |  | 1920 - 1923 | Doctor of Medical Sciences | founder of Russian clinical neurogenetics Member of the Academy of Medical Sciences of the USSR |
| 3 | Alexander Dmitrievich Gulyaev |  | 1923 - 1926 | | |
| four | Tagi Shahbazi |  | 1926 - 1929 | not | Writer |
| five | Vladimir Sergeevich Elpatyevsky | | 1929 | | |
| 6 | Maxud Mamedov |  | 1929 - 1930 | | |
| 1930-1934 The University is abolished, in its place the Higher Pedagogical Institute functioned. |
|---|
| 7 | Mamed Kyazim Alekperli |  | 1934 - 1935 | | Literary critic, philosopher |
| eight | Bala bey Hasanbekov | | 1935 - 1937 | | |
| 9 | Aziz Aliyev |  | 1937 | Doctor of Medical Sciences | |
| ten | Jebrail Aleskerov | | 1937 - 1941 | | |
| eleven | Shamil Aliyev | | 1941 - 1944 | | |
| 12 | Abdulla Karaev | | 1944 - 1950 | Doctor of Medical Sciences | Academician of the Academy of Sciences of Azerbaijan SSR |
| 13 | Jafar Hajiyev | | 1950 - 1954 | | |
| 14 | Yusif Mamedaliyev |  | 1950 - 1954 | Doctor of Chemical Sciences | Academician of the Academy of Sciences of Azerbaijan SSR |
| 15 | Shafayat Mehdiyev | | 1958 - 1965 | Doctor of Geological and Mineralogical Sciences | Academician of the Academy of Sciences of Azerbaijan SSR |
| sixteen | Mehdi Aliyev | | 1965 - 1970 | | |
| 17 | Faik Bagirzade | | 1970 - 1987 | Doctor of Geological and Mineralogical Sciences | Academician of the Academy of Sciences of Azerbaijan SSR |
| 18 | Yahya Mamedov | | 1987 - 1989 | | |
| nineteen | Jamil Guliyev | | 1989 - 1990 | Doctor of Historical Sciences | Academician of the Academy of Sciences of Azerbaijan SSR |
| 20 | Mirabbas Gasimov | | 1990 - 1992 | Doctor of Physics and Mathematics | Corresponding member of ANAS |
| 21 | Firudin Samandarov | | 1992 - 1993 | Doctor of Law | |
| 22 | Murtuz Aleskerov | | 1993 - 1996 | Doctor of Law | |
| 23 | Misir Mardanov | | 1996 - 1998 | Doctor of Physics and Mathematics | Corresponding member of ANAS |
| 24 | Abel Maharramov | | 1999 - 2018 | Doctor of Chemical Sciences | Academician of ANAS |