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Elosulfase Alpha

Elosulfase alpha is a recombinant N-acetylgalactosamine-6-sulfatase enzyme used to treat IVA mucopolysaccharidosis ( Morkio A syndrome ). Got the status of an orphan drug and is approved for use: USA (2014). [one]

Elosulfase Alpha
Chemical compound
Gross formulaC 5020 H 7588 N 1364 O 1418 S 34  
Molar mass110.8 kDa
Cas
Drugbank
Classification
ATX
Other names
Vimizim (Vimizim)

Mechanism of Action

Similar N- acetylgalactosamine-6-sulfatase.

Indications

Mucopolysaccharidosis IVA (Morkio A syndrome). [2]

Notes

  1. ↑ CDER New Molecular Entity (NME) and Biologic Approvals Calendar Year 2014 . FDA
  2. ↑ VIMIZIM- elosulfase alfa injection, solution, concentrate .
Source - https://ru.wikipedia.org/w/index.php?title=Elosulfase_alpha&oldid=69825179


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