Metreleptin is a synthetic adipokine leptin used to treat lipodystrophy . Gained orphan drug status and approved by the FDA in 2014 [1]
| Metreleptin | |
|---|---|
| Chemical compound | |
| Gross formula | C 714 H 1167 N 191 O 221 S 6 |
| Molar mass | 16,156 daltons |
| Cas | |
| Drugbank | |
| ATX | |
| Other names | |
| Myalept | |
Mechanism of Action
Activates the leptin receptor. [2]
Indications
Leptin deficiency in patients with congenital or acquired generalized lipodystrophy. [2]