Acidosis (from the Latin. Acidus - acid ) - the shift of the acid-base balance of the body towards an increase in acidity (decrease in pH ).
Acidosis | |
---|---|
ICD-10 | E 87.2 |
ICD-9 | 276.2 |
ICD-9-KM | |
DiseasesDB | 87 |
MedlinePlus | |
Mesh | D000138 |
Content
Symptoms of acidosis
- headaches
- drowsiness
- dyspnea
- cough
- arrhythmia
- cardiopalmus
- weakness and cramps
- diarrhea
- nausea and vomiting
Causes of Acidosis
Usually, oxidation products of organic acids are rapidly removed from the body. In febrile diseases , intestinal disorders, pregnancy , fasting , etc., they are retained in the body, which is manifested in mild cases by the appearance in the urine of acetoacetic acid and acetone (so-called acetonuria ), and in severe cases (for example, diabetes mellitus ) can result to coma .
Classification of acidosis
Depending on the value of the pH :
- compensated acidosis : the blood pH does not fall below the limit of the physiological norm (7.35). Heartbeat increases, breathing becomes faster, and blood pressure rises;
- subcompensated acidosis ( lat. acidosis subcompensata ): the pH level of the blood is in the range of 7.34-7.25. May cause cardiac depression, even cardiac arrhythmias . There is shortness of breath , often vomiting and diarrhea ;
- uncompensated acidosis : pH is below the physiological norm (less than 7.24). Decompensated acidosis. Causes disorders of the central nervous system ( dizziness , drowsiness , loss of consciousness ), cardiovascular system , gastrointestinal tract , etc.
By origin:
- gas acidosis ( lat. acidosis gasea ). Occurs when hypoventilation or inhalation of air with a high content of carbon dioxide . Respiratory , respiratory ;
- non-gas acidosis ( lat. acidosis ingasea ):
- metabolic acidosis ( lat. acidosis metabolica ). Occurs due to the accumulation of acidic products in the tissues, insufficient binding or destruction ( ketoacidosis , lactic acidosis ). Exchange acidosis;
- secretory acidosis ( lat. acidosis excretoria ). Occurs with the difficulty of removing non-volatile acids by the kidneys (renal acidosis) or increased loss of bases through the gastrointestinal tract (gastroenteric acidosis);
- exogenous acidosis ( lat. acidosis exogena ). Occurs with the introduction into the body of a large number of acids or substances that form acids in the process of metabolism ;
- mixed acidosis ( lat. acidosis mixta ). The combination of different types of acidosis. For example, in the pathology of the cardiovascular or respiratory systems, the removal of carbon dioxide is difficult, which causes a decrease in oxygen in the blood and the subsequent accumulation of oxidized metabolic products.
Treatment
Elimination of the cause of acidosis (for example, insulin deficiency in diabetes).
See also
- Alkalosis
- Kussmaul's breath
- Acetonemic syndrome in children
- Ketoacidosis
Notes
- β Monarch Disease Ontology release 2018-06-29sonu - 2018-06-29 - 2018.
Literature
References Used
- Acidosis // The Small Medical Encyclopedia, V. 1 - M .: Soviet Encyclopedia, 1991 - p. 193-1945 - ISBN 5-85270-040-1
Links
- Acetonuria // Encyclopedic Dictionary of Brockhaus and Efron : in 86 tons (82 tons and 4 extra). - SPb. , 1890-1907.