3-Phosphoglyceric acid ( 3-FGK , 3-phosphoglycerate ) is an organic compound, an ester of glyceric acid and phosphoric acid , an important intermediate metabolite of glycolysis and the Calvin cycle . In the Calvin cycle, 3-phosphoglycerate is formed as a result of spontaneous decomposition of an unstable six-carbon compound formed as a result of CO 2 fixation on a ribulose-1,5-bisphosphate molecule . Thus, for each molecule of fixed CO 2 two molecules of 3-phosphoglycerate are formed [1] .
| 3-phosphoglycerate | |
|---|---|
 | |
 | |
| Are common | |
| Systematic name | (2 R ) -2-Hydroxy-3-phosphonooxypropanoic acid |
| Abbreviations | 3-FCG |
| Chem. formula | C 3 H 7 O 7 P 1 |
| Physical properties | |
| Molar mass | 186.06 g / mol |
| Classification | |
| Reg. CAS number | 820-11-1 |
| PubChem | |
| Smiles | |
| Inchi | |
| Chebi | 17794 |
Content
Glycolysis
| 1,3-diphospho- D- glycerate | Phosphoglycerate kinase | 3-phospho- D- glycerate | Phosphoglyceromutase | 2-phospho- D- glycerate | ||
| ADP | ATP | |||||
| ADP | ATP | |||||
| Phosphoglycerate kinase | Phosphoglyceromutase | |||||
Calvin's cycle
During the dark reactions (Calvin cycle), two 3-FHA molecules are formed, some of which return to the cycle and regenerate to ribulose-1,5-diphosphate , and the other is reduced to glyceraldehyde-3-phosphate . This is the first product formed during the reactions of the Calvin cycle [2] .
Amino Acid Synthesis
In addition, 3-phosphoglycerate is a precursor for the synthesis of serine , which in turn serves as a precursor for the synthesis of cysteine and glycine in the homocysteine cycle [3] .
See also
- 2-phosphoglycerate
Notes
- ↑ Shvedova, 2004 , p. 244.
- ↑ Shvedova, 2004 , p. 217.
- ↑ Shvedova, 2004 , p. 401.
Literature
- V.P. Komov, V.N. Shvedova. Biochemistry. - “Bustard”, 2004. - 638 p.