Pindobind - a research substance patented by IBM . [1] It is a strong, highly potent antagonist of 5-HT 1A receptors , and binds covalently and irreversibly to them by alkylating the receptor . In the experiment, it exhibits the properties of a CNS depressant [2] In particular, it reduces the aggressiveness of animals, and at the same time reduces the tendency of animals to avoid and run away. [2]
| Pindobind | |
|---|---|
| Chemical compound | |
| Gross formula | C 23 H 34 BrN 3 O 3 |
| CAS | |
| Pubchem | |
Notes
- ↑ PubChem 4827
- ↑ 1 2 Bell, R; Hobson, H. Effects of pindobind 5-hydroxytryptamine1A (5-HT1A), a novel and potent 5-HT1A antagonist, on and albon mice (English) // Pharmacology, Biochemistry, and Behavior : journal. - 1993. - Vol. 46 , no. 1 . - P. 67-72 . - DOI : 10.1016 / 0091-3057 (93) 90318-N . - PMID 8255924 .