| M | Team | AND | AT | N | P | Balls | ± | ABOUT | Notes |
|---|
| one | Jeunesse Ash | 22 | sixteen | one | five | 43 - 25 | +18 | 33 | First round of the 1980/81 Champions Cup |
| 2 | Red Boys Differdange | 22 | 14 | four | four | 52 - 21 | +31 | 32 | First round of the UEFA Cup 1980/81 |
| 3 | Progress Nyderkorn | 22 | eleven | eight | 3 | 58 - 28 | +30 | thirty |
| four | Union Luxembourg | 22 | 12 | five | five | 48 - 29th | +19 | 29th |
| five | Grevenmacher | 22 | 6 | ten | 6 | 27 - 32 | −5 | 22 |
| 6 | Stud Dudelange | 22 | 7 | five | ten | 29th - 33 | −4 | nineteen |
| 7 | Dispute Luxembourg | 22 | 6 | 7 | 9 | 29th - 33 | −4 | nineteen | First round of the 1980/81 Cup Cup |
| eight | Abner | 22 | 7 | four | eleven | 33 - 33 | 0 | 18 |
| 9 | Aris Bonnevoy | 22 | 6 | 6 | ten | 26 - 36 | −10 | 18 |
| ten | Etzella | 22 | 7 | 3 | 12 | thirty - 44 | −14 | 17 |
| eleven | Sherre Rodange | 22 | 6 | four | 12 | 18 - 44 | −26 | sixteen | Departure to the Honorary Division |
| 12 | Rumelange | 22 | four | 3 | 15 | 21 - 56 | −35 | eleven |
And - games, B - wins, N - draws, P - losses, Goals - goals scored and goals conceded, ± - goal difference, O - points
Jeunesse Ash (17th time)
Red Boys Differdange
Progress Nyderkorn