Medicine of the 21st century ) using vitrification .
Content
Company
The company was founded in 1993. The team of "Medicine of the 21st Century" conducted the world's first successful cryopreservation and thawing of a rabbit kidney. [one]
Dr. Gregory M. Faye, the first person to use vitrification in reproductive cryopreservation [2] [3] [4] [5] [6] [7] [8] [9] [10] , is a member of the board of directors of the company responsible for prioritization, planning and management of scientific activities. He also leads all joint research projects carried out in collaboration with external organizations (universities, industrial and research companies) to develop specific products and services.
The company holds a large number of patents - mainly for cryoprotective compounds, which significantly reduce ice formation and are minimally toxic , as well as synthetic ice blockers, which are an inexpensive substitute for protein that prevents tissue freezing in polar organisms . The company's website contains a list of publications of its employees in scientific journals based on studies conducted in the company's laboratories. [eleven]
In 2004, 21st Century Medicine received a $ 900,000 grant from the US National Institutes of Health to study a preservative solution developed by the University of Rochester (New York) to increase the shelf life of donor hearts. [12]
At the annual conference of the Society of Cryobiologists in July 2005, representatives of the Medicine of the 21st Century company announced a successful experience in vitrifying a rabbit kidney to a temperature of -135 ° C using a cryoprotective solution of its own design. After thawing, the kidney was successfully transplanted into the rabbit and functioned for a long time. [13]
See also
- Vitrification
- Cryobiology
- Cryopreservation
- Cryonics
- Organ transplant
Notes
- ↑ Fahy GM, Wowk B., Pagotan R., Chang A., Phan J., Thomson B., Phan L. Physical and biological aspects of renal vitrification (English) // ORGANOGENESIS: journal. - 2009. - Vol. 5 , no. 3 . - P. 167-175 . - DOI : 10.4161 / org.5.3.9974 . - PMID 20046680 .
- ↑ Michael J. Taylor, Ying C. Song, and Kelvin GM Brockbank. Vitrification in Tissue Preservation: New Developments In: Life in the Frozen State (BJ Fuller, N. Lane, and EE Benson, Eds.). - CRC Press , 2004. - P. 603–641. - ISBN 0-415-24700-4 .
- ↑ Fahy, GM and Hirsh, A. Prospects for Organ Preservation by Vitrification. In: Organ Preservation, Basic and Applied Aspects (DE Pegg, IA Jacobsen and NA Halasz, Eds.). - Springer , 1982. - P. 399–404. - ISBN 0-85200-418-4 .
- ↑ Fahy GM, MacFarlane DR, Angell CA, Meryman HT Vitrification as an approach to cryopreservation (neopr.) // Cryobiology. - 1984. - T. 21 , No. 4 . - S. 407-426 . - DOI : 10.1016 / 0011-2240 (84) 90079-8 . - PMID 6467964 .
- ↑ Rall WF, Fahy GM Ice-free cryopreservation of mouse embryos at -196 degrees C by vitrification (Eng.) // Nature : journal. - 1985. - Vol. 313 , no. 6003 - P. 573-575 . - DOI : 10.1038 / 313573a0 . - PMID 3969158 .
- ↑ Fahy GM Vitrification: a new approach to organ cryopreservation (English) // PROGRESS IN CLINICAL AND BIOLOGICAL RESEARCH: journal. - 1986. - Vol. 224 . - P. 305—335 . - PMID 3540994 .
- ↑ Fahy, Gregory M. Vitrification versus Freezing of Organs . Science (journal) E-Letter responses . American Association for the Advancement of Science (May 16, 2002). Date of treatment October 22, 2010.
- ↑ Fahy, GM, and Rall, WF Vitrification: An overview. In: Vitrification in Assisted Reproduction: A User's Manual and Troubleshooting Guide (J. Liebermann and MJ Tucker, Eds). - Informa Healthcare, 2007. - ISBN 0-415-40882-2 .
- ↑ Mullen, SF, and Fahy, GM Fundamental aspects of vitrification as a method of reproductive cell, tissue, and organ cryopreservation. In: Principles & Practice of Fertility Preservation (Donnez, J., and Kim, SS, Eds.). - Cambridge University Press , February 28, 2011 .-- ISBN 0-521-19695-7 .
- ↑ Cryopreservation of embryos (English) // The Lancet : journal. - Elsevier , 1985 .-- Vol. 1 , no. 8430 . - P. 678 . - DOI : 10.1016 / s0140-6736 (85) 91336-4 . - PMID 2858625 .
- ↑ 21CM Publications . Date of treatment November 8, 2006. Archived October 18, 2006.
- ↑ NIH grant to be used for heart preservation research . Business Wire (October 31, 2004). Date of treatment May 2, 2012.
- ↑ Plenary Session: Fundamentals of Biopreservation . CRYO 2005 Scientific Program . Society for Cryobiology (July 24, 2005). Date of treatment November 8, 2006. Archived August 30, 2006.