TUG1 (taurine upregulated gene 1) is a long non-coding RNA that is expressed in the retina and brain . It was first identified when searching for genes that are activated in the cells of the developing retina in response to the action of taurine . TUG1 gene product .
| TUG1 | |
|---|---|
| Designations | |
| Characters | TUG1 ; FLJ20618, LINC00080, NCRNA00080 |
| Entrez gene | 55,000 |
| Hgnc | 26066 |
| OMIM | 614971 |
| Refseq | NR_002323 |
| Other data | |
| Locus | 22nd hr. , 22q12.2 |
Necessary for the normal development of retinal photoreceptors. [1] The level of gene expression is elevated in Huntington's disease . [2]
See also
- Xist
Notes
- ↑ Young TL, Matsuda T., Cepko CL. The noncoding RNA taurine upregulated gene . Biol. : journal. - 2005. - March ( vol. 15 , no. 6 ). - P. 501-512 . - DOI : 10.1016 / j.cub.2005.02.027 . - PMID 15797018 .
- ↑ Johnson, R. Long non-coding RNAs in Huntington's disease neurodegeneration. (English) // Neurobiol Dis : journal. - 2012. - May ( vol. 46 , no. 2 ). - P. 245-254 . - DOI : 10.1016 / j.nbd.2011 . 12.006 . - PMID 22202438 .
Literature
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