Lutetium isotopes

Lutetium isotopes are varieties of the chemical element of lutetium with different numbers of neutrons in the nucleus . Lutetium isotopes are known with mass numbers from 150 to 184 (the number of protons 71, neutrons from 79 to 113) and 18 nuclear isomers .

Natural lutetium consists of a mixture of two isotopes . One stable:

¹⁷⁵ Lu ( isotopic prevalence 97.41%)

And one with a huge half-life commensurate with the age of the universe :

¹⁷⁶ Lu (isotopic abundance 2.59%, half-life 3.78⋅10 ¹⁰ years, beta decay , daughter hafnium-176 isotope).

Due to the radioactivity of ¹⁷⁶ Lu, natural lutetium has a specific activity of about 52 kBq / kg. ^[one]

Lutetium-176

Radioactive ¹⁷⁶ Lu is used in one of the methods of nuclear geo- and cosmochronology ( lutetium-hafnium dating ).

¹⁷⁶ Lu is the starting isotope for the synthesis of ¹⁷⁷ Lu. In Russia, production of ¹⁷⁶ Lu by isotope enrichment from natural lutetium has been established. ^[2]

Lutetium-177

In the 2010s, ¹⁷⁷ Lu began to be used in medicine for the treatment of tumor diseases, in particular the prostate and neuroendocrine tumors. ^[3] ^{[4] A} drug containing lutetium-177 selectively accumulates in the affected tissues, where the beta radiation of the isotope has a local inhibitory effect on nearby tissues. In 2018, in Russia, the Institute of Reactor Materials produces the ¹⁷⁷ Lu isotope by neutron irradiation of targets from highly enriched ¹⁷⁶ Lu. Work is underway to prepare the industrial production of a precursor of radiopharmaceuticals (lutetium trichloride) that meets GMP requirements. ^[five]

Lutetium Isotope Table

Symbol nuclide	Z ( p )	N ( n )	Isotope mass ^[6] ( a.m. )	Period half-life ^[7] (T _1/2 )	Back and parity kernels ^[7]
Symbol nuclide	Excitation energy			Period half-life ^[7] (T _1/2 )	Back and parity kernels ^[7]
¹⁵⁰ Lu	71	79	149.97323	43 ms	2+
^150m Lu	34 keV			80 µs	one
¹⁵¹ Lu	71	80	150.96758	80.6 ms	11 / 2-
^151m Lu	77 keV			16 μs	3/2 +
¹⁵² Lu	71	81	151.96412	650 ms	five-
¹⁵³ Lu	71	82	152,95877	900 ms	11 / 2-
^153m1 Lu	80 keV			1 s	1/2 +
^153m2 Lu	2,5025 MeV			100 ns	23 / 2-
^153m3 Lu	2.6329 MeV			15 μs	27 / 2-
¹⁵⁴ Lu	71	83	153.95752	1 s	2-
^154m1 Lu	58 keV			1.12 s	9+
^154m2 Lu	2.562 MeV			35 μs	17+
¹⁵⁵ Lu	71	84	154.954316	68.6 ms	11 / 2-
^155m1 Lu	20 keV			138 ms	1/2 +
^155m2 Lu	1.7810 MeV			2.70 ms	25 / 2-
¹⁵⁶ Lu	71	85	155,95303	494 ms	2-
^156m Lu	220 keV			198 ms	9+
¹⁵⁷ Lu	71	86	156,950098	6.8 seconds	1/2 +
^157m Lu	21.0 keV			4.79 s	11 / 2-
¹⁵⁸ Lu	71	87	157,949313	10.6 s	2-
¹⁵⁹ Lu	71	88	158.94663	12.1 seconds	1/2 +
^159m Lu	100 keV			10 s	11 / 2-
¹⁶⁰ Lu	71	89	159.94603	36.1 seconds	2-
^160m Lu	0 keV			40 s
¹⁶¹ Lu	71	90	160,94357	77 s	1/2 +
^161m Lu	166 keV			7.3 ms	9 / 2-
¹⁶² Lu	71	91	161.94328	1.37 min	one-
^162m1 Lu	120 keV			1.5 min	four-
^162m2 Lu	300 keV			1.9 min
¹⁶³ Lu	71	92	162.94118	3.97 min	1/2 +
¹⁶⁴ Lu	71	93	163.94134	3.14 min	one-
¹⁶⁵ Lu	71	94	164,939407	10.74 min	1/2 +
¹⁶⁶ Lu	71	95	165,93986	2.65 min	6-
^166m1 Lu	34.37 keV			1.41 min	3-
^166m2 Lu	42.9 keV			2.12 min	0-
¹⁶⁷ Lu	71	96	166,93827	51.5 min	7/2 +
^167m Lu	0 keV			1 minute	1 / 2-
¹⁶⁸ lu	71	97	167,93874	5.5 min	6-
^168m Lu	180 keV			6.7 min	3+
¹⁶⁹ Lu	71	98	168,937651	34.06 h	7/2 +
^169m Lu	29.0 keV			160 s	1 / 2-
¹⁷⁰ Lu	71	99	169.938475	2,012 days	0+
^170m Lu	92.91 keV			670 ms	four-
¹⁷¹ Lu	71	100	170,9379131	8.24 days	7/2 +
^171m Lu	71.13 keV			79 s	1 / 2-
¹⁷² Lu	71	101	171.939086	6,70 days	four-
^172m1 Lu	41.86 keV			3.7 min	one-
^172m2 Lu	65.79 keV			332 ns	1+
^172m3 Lu	109.41 keV			440 μs	1+
^172m4 Lu	213.57 keV			150 ns	6-
¹⁷³ Lu	71	102	172,9389306	1.37 years	7/2 +
^173m Lu	123.672 keV			74.2 μs	5 / 2-
¹⁷⁴ Lu	71	103	173,9403375	3.31 years	one-
^174m1 Lu	170.83 keV			142 days	6-
^174m2 Lu	240.818 keV			395 ns	3+
^174m3 Lu	365,183 keV			145 ns	four-
¹⁷⁵ Lu	71	104	174,9407718	stable	7/2 +
^175m1 Lu	1.3922 MeV			984 μs	19/2 +
^175m2 Lu	353.48 keV			1.49 μs	5 / 2-
¹⁷⁶ Lu	71	105	175.9426863	3.85⋅10 ¹⁰ years	7-
^176m Lu	122.855 keV			3,664 h	one-
¹⁷⁷ Lu	71	106	176,9437581	6.6475 d	7/2 +
^177m1 Lu	150.3967 keV			130 ns	9 / 2-
^177m2 Lu	569.7068 keV			155 μs	1/2 +
^177m3 Lu	970.1750 keV			160.44 days	23 / 2-
^177m4 Lu	3.90 MeV			7 min	39 / 2-
¹⁷⁸ Lu	71	107	177,945955	28.4 min	1+
^178m Lu	123.8 keV			23.1 min	9-
¹⁷⁹ Lu	71	108	178,947327	4.59 h	7/2 +
^179m Lu	592.4 keV			3.1 ms	1/2 +
¹⁸⁰ Lu	71	109	179,94988	5.7 min	5+
^180m1 Lu	13.9 keV			1 s	3-
^180m2 Lu	624.0 keV			1 ms	9-
¹⁸¹ Lu	71	110	180.95197	3.5 min	7/2 +
¹⁸² Lu	71	111	181.95504	2.0 min	one
¹⁸³ Lu	71	112	182.95757	58 s	7/2 +
¹⁸⁴ Lu	71	113	183,96091	20 s	3+

Notes

↑ Assessment of the radiological significance of rare earth metals having natural radioactive isotopes. E.P. Lisachenko. St. Petersburg Scientific Research Institute of Radiation Hygiene named after Professor P.V. Ramzayev, St. Petersburg
↑ Use of stable isotopes in nuclear medicine
↑ Iridium-based radiation sources, radiopharmaceutical precursor lutetium trichloride and iodine-125 radioisotope for nuclear medicine
↑ Isotope therapy of lutetium 177-PSMA
↑ Big business recognized the merits of Rosatom
↑ Data shown for Audi G. , Wapstra AH , Thibault C. The AME2003 atomic mass evaluation (II). Tables, graphs, and references (Eng.) // Nuclear Physics A. - 2003. - Vol. 729 . - P. 337–676 . - DOI : 10.1016 / j.nuclphysa.2003.11.003 . - .
↑ ¹ ² Data are given for Audi G. , Bersillon O. , Blachot J. , Wapstra AH The NUBASE evaluation of nuclear and decay properties // Nuclear Physics A. - 2003. - T. 729 . - S. 3—128 . - DOI : 10.1016 / j.nuclphysa.2003.11.001 . - .

Isotopes of ytterbium Periodic table on the isotopes of elements Hafnium isotopes

one
H

2
He

3
Li

four
Be

five
B

6
C

7
N

eight
O

9
F

ten
Ne

eleven
Na

12
Mg

13
Al

14
Si

15
P

sixteen
S

17
Cl

18
Ar

nineteen
K

20
Ca

21
Sc

22
Ti

23
V

24
Cr

25
Mn

26
Fe

27
Co

28
Ni

29
Cu

thirty
Zn

31
Ga

32
Ge

33
As

34
Se

35
Br

36
Kr

37
Rb

38
Sr

39
Y

40
Zr

41
Nb

42
Mo

43
Tc

44
Ru

45
Rh

46
Pd

47
Ag

48
Cd

49
In

50
Sn

51
Sb

52
Te

53
I

54
Xe

55
Cs

56
Ba

*

72
Hf

73
Ta

74
W

75
Re

76
Os

77
Ir

78
Pt

79
Au

80
Hg

81
Tl

82
Pb

83
Bi

84
Po

85
At

86
Rn

87
Fr

88
Ra

**

104
Rf

105
Db

106
Sg

107
Bh

108
Hs

109
Mt

110
Ds

111
Rg

112
Cn

113
Nh

114
Fl

115
Mc

116
Lv

117
Ts

118
Og

*

57
La

58
Ce

59
Pr

60
Nd

61
Pm

62
Sm

63
Eu

64
Gd

65
Tb

66
Dy

67
Ho

68
Er

69
Tm

70
Yb

71
Lu

**

89
Ac

90
Th

91
Pa

92
U

93
Np

94
Pu

95
Am

96
Cm

97
Bk

98
Cf

99
Es

100
Fm

101
Md

102
No

103
Lr

[1] Assessment of the radiological significance of rare earth metals having natural radioactive isotopes. E.P. Lisachenko. St. Petersburg Scientific Research Institute of Radiation Hygiene named after Professor P.V. Ramzayev, St. Petersburg

[2] Use of stable isotopes in nuclear medicine

[3] Iridium-based radiation sources, radiopharmaceutical precursor lutetium trichloride and iodine-125 radioisotope for nuclear medicine

[4] Isotope therapy of lutetium 177-PSMA

[5] Big business recognized the merits of Rosatom

[AME2003-6] Data shown for Audi G. , Wapstra AH , Thibault C. The AME2003 atomic mass evaluation (II). Tables, graphs, and references (Eng.) // Nuclear Physics A. - 2003. - Vol. 729 . - P. 337–676 . - DOI : 10.1016 / j.nuclphysa.2003.11.003 . - .

[Nubase2003-7] ¹ ² Data are given for Audi G. , Bersillon O. , Blachot J. , Wapstra AH The NUBASE evaluation of nuclear and decay properties // Nuclear Physics A. - 2003. - T. 729 . - S. 3—128 . - DOI : 10.1016 / j.nuclphysa.2003.11.001 . - .

Lutetium isotopes

Lutetium-176

Lutetium-177

Lutetium Isotope Table

Notes

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