Gunin, Andrei Germanovich

In 1982 he graduated from high school number 28 in the city of Cheboksary with a gold medal. In 1988 he graduated with honors from the medical faculty of Chuvash State University with a degree in General Medicine. From 1988 to 1990, he worked as an obstetrician-gynecologist at the Cheboksary City Maternity Hospital. Since 1991 - works concurrently as an obstetrician-gynecologist at the obstetric department of the Cheboksary city maternity hospital (1989-1999), Municipal hospital "Builders Hospital" (1999-2001), Municipal hospital "5 City Hospital" (since 2001). 1990-1997 - Assistant / Senior Lecturer / Associate Professor, 1998-2003 Professor, Department of Histology, Medical Institute, Chuvash State University. Since 2003, professor at the Department of Obstetrics and Gynecology, Medical Institute of the Chuvash State University. July – September 1995 - internship, Department of Dermatology, Humboldt University, Berlin, Germany.

Candidate of Medical Sciences since 1990, defense of the dissertation - June 11, 1990 at Moscow Medical University. N. I. Pirogova, PhD thesis: Morphological basis of histamine-estrogen relationships in the uterus of rats.

Doctor of Medical Sciences since 1997., defense of the dissertation - November 29, 1996 at the Peoples' Friendship University of Russia (Moscow), doctoral dissertation: Estrogen-induced histogenesis in the uterus with endocrine imbalance.

The academic title of professor was awarded in 2000. The highest qualification category in the specialty "Obstetrics and Gynecology" (2001). Specialist Certificate in Obstetrics and Gynecology (2004). Soros professor (2000, 2001). Member of the New York Academy of Sciences (1996). Member of the International Society of Neuroendocrinologists since 1999. He is included in the guide Who's Who in the World - 1999, 2001. Member of the editorial board of the journal Health Care in Chuvashia since 2004. Member of the editorial board of European Journal of Obstetrics & Gynecology and Reproductive Biology since 2005.

Pregnancy management, including high-risk pregnancy. Management of normal and pathological birth, including surgical delivery. Menstrual irregularities. Inflammatory diseases of the female genital organs. Neuroendocrine pathology. Headache, asthenic syndrome, post-stress disorders.

Scientific work in the field of fundamental experimental endocrinology of the female reproductive system. Studies are aimed at identifying the patterns and regulatory mechanisms of the action of female sex hormones - estrogen on the uterus, where these hormones not only cause normal physiological reactions, but also contribute to the development of malignant tumors. Studies have established for the first time the role of acute and chronic stress, prolactin, growth hormone, heparin, histamine and its receptor blockers, mast cells, glucocorticoid hormones in the action of estrogen hormones on the uterus.

Scholarship of the President of the Chuvash Republic, grants from the Competition Center for Fundamental Natural Sciences at St. Petersburg State University of the Ministry of Education of the Russian Federation; grants from the Russian Foundation for Basic Research (RFBR), a grant from the President of the Russian Federation for young doctors of science, a grant from the Ministry of Education and Science of the Russian Federation under the program Universities of Russia, a grant from the Chuvash State University

INTAS, International Journal of Gynecological Cancer, European Journal of Obstetrics & Gynecology and Reproductive Biology, Biology of Reproduction, Reproduction, Molecular Human Reproduction, Endocrine, Journal of Pharmacy & Pharmaceutical Sciences

• Sysoeva L.A., Gunin A.G. On the affiliation of luminescent monoamine-containing spleen cells to the APUD system. Experimental and applied morphology. Cheboksary: ​​Chuvash. University, 1988, 16-19
• Gordon D.S., Gunin A.G. Localization of histamine in rat uterus structures. Archive of Anatomy, Histology and Embryology, 1988, 95, N 12, 66-68
• Gunin A.G. Distribution of histamine in the structures of the uterus of ovariectomized rats with the introduction of estradiol, histamine antagonists and an inhibitor of prostaglandin biosynthesis. Archive of Anatomy, Histology and Embryology, 1989, 97, N 11, 82-86
• Gunin A.G., Gordon D.S. Affiliation of granular biogenic amines containing rat endometrial cells to the mononuclear phagocyte system. Archive of Anatomy, Histology and Embryology, 1990, 98, N 1, 68-70
• Gunin A.G., Gordon D.S., Vazina I.R. Histamine content and functional activity of alveolar macrophages. Immunology, 1990, N 6, 12-13
• Gunin A.G., Gordon D.S., Semenov V.D. Influence of estradiol on histamine distribution in rat uterus structures is normal and during experimental hormone administration. Problems of Endocrinology, 1991, 37, N 4, 49-51
• Gunin A.G., Gordon D.S. Luminescent-histochemical method for determining the activity of histidine decarboxylase in tissue structures. Fluorescent research methods and clinical diagnostics. Moscow, 1992, 25
• Sergeeva V.E., Gordon D.S., Gunin A.G. Combination of the properties of macrophages and APUD-series cells in monoamine-containing premedullary thymic lobule cells. Morphology, 1994, 106, No. 1-3: 159-163
• Gunin A. Realization of estradiol effects in the uterus of ovariectomized rats under acute stress. European Journal of Obstetrics & Gynecology and Reproductive Biology, 1995, 60, 69-74
• Gunin A. The role of prolactin in realization of estradiol action in the uterus of ovariectomized rats. European Journal of Obstetrics & Gynecology and Reproductive Biology, 1996, 64, 119-127
• Gunin A. Effect of chronic stress on estradiol action in the uterus of ovariectomized rats. European Journal of Obstetrics & Gynecology and Reproductive Biology, 1996, 66, 169–174
• Gunin A, Handjiski B, Reichrath J, Eichmuller S, Henz BM, Paus R. Hair cycle-associated changes in cell proliferation: new findings in the CB57L / 6 mouse model. Archives of Dermatological Research, 1996, 288, 310
• Gunin A. Prolactin takes part in the increase of expression of estradiol effects in the rat uterus under chronic stress: Abstr 10th International Congress of Endocrinology, 12-15 June 1996, San Francisco, USA. San Francisco, 1996, 2, 843
• Gunin A. Influence of growth hormone on the uterine response to oestradiol in rats. Journal of Reproduction and Fertility, 1997, 110, 299-306
• Gunin AG. Effect of heparin on oestradiol-induced cell growth and proliferation in the uterus of ovariectomized rats. Journal of Endocrinology, 1997, 154, 441-448
• Gunin AG, Sharov AA. Role of mast cells in oestradiol effects in the uterus of ovariectomized rats. Journal of Reproduction and Fertility, 1998, 113, 61-68
• Gunin AG. Effect of long-term glucocorticoid treatment on oestradiol-induced proliferation in the uterus of ovariectomized rats. Journal of Endocrinology, 1998, 157, 481–488
• Gunin AG, Nikolaev DV. Effect of acute and chronic glucocorticoid treatments on epithelial cell proliferation in the esophagus and small intestine of rats. Journal of Gastroenterology, 1999, 34, 661–667
• Gunin AG, Sharov AA, Nikolaev DV. Two month glucocrticoid treatment increases in estradiol-induced stromal and myometrial cell proliferation in the uterus of ovariectomized rats. European Journal of Obstetrics & Gynecology and Reproductive Biology, 2000, 88, 171-179
• Gunin AG, Nikolaev DV. Two month glucocorticoid treatment increases in proliferation in the stomach and large intestine of rats. Digestion, 2000, 61: 151-156
• Gunin AG. Estrogen changes mitosis orientation in the uterine epithelia. European Journal of Obstetrics & Gynecology and Reproductive Biology, 2001, 97, N 1, 82-86
• Gunin AG, Mashin IN, Zakharov DA. Proliferation, mitosis orientation and morphogenetic changes in the uterus of mice following chronic treatment with both estrogen and glucocorticoid hormones. Journal of Endocrinology, 2001, 169, 23-31
• Gunin AG, Emelianov VIu, Tolmachev AS, Tolmacheva AIu. Effect of prolactin and dopaminergic drugs on uterine response to chronic estrogen exposure. Journal of Endocrinology, 2002, 172, 61-69
• Gunin AG, Emelianov V, Tolmachev AS. Effect of adrenocorticotropic hormone on the development of oestrogen-induced changes and hyperplasia formation in mouse uterus. Reproduction, 2002, 123, 601-611
• Gunin AG, Emelianov VU, Tolmachev AS. Expression of estrogen receptor-alpha, glucocorticoid receptor, beta-catenin and glycogen synthase kinase-3-beta in the uterus of mice following long-term treatment with estrogen and glucocorticoid hormones. European Journal of Obstetrics & Gynecology and Reproductive Biology, 2003, 107, 1, 62-67
• Tobin DJ, Gunin A, Magerl M, Handijski B, Paus R. Plasticity and cytokinetic dynamics of the hair follicle mesenchyme: implications for hair growth control. Journal of Investigative Dermatology, 2003, 120, 895–904
• Gunin AG, Emelianov VU, Mironkin IU, Morozov MP, Ivanov VA. Uterine response to estradiol under action of chorionic gonadotropin in mice. International Journal of Gynecological Cancer, 2003, 13, N4, 485–496
• Gunin AG, Emelianov VU, Mironkin IU, Morozov MP, Tolmachev AS. Lithium treatment enhances estradiol-induced proliferation and hyperplasia formation in the uterus of mice. European Journal of Obstetrics & Gynecology and Reproductive Biology, 2004, 114, 83-91
• Gunin AG, Bitter AD, Demakov AB, Vasilieva EN, Suslonova NV. Effects of peroxisome proliferator activated receptors alpha and gamma agonists on estradiol-induced proliferation and hyperplasia formation in the mouse uterus. Journal of Endocrinology, 2004, 182, 229-239
• Gunin AG, Kapitova IN, Suslonova NV. Effects of histone deacetylase inhibitors on estradiol-induced proliferation and hyperplasia formation in the mouse uterus. Journal of Endocrinology, 2005, 185, 539-549
• Gunin A.G. Histology in tables and diagrams: Textbook (Recommended by UMO). Moscow: Medical News Agency, 2005, 192 pp., ISBN 5-89481-288-7 .
• Sharapova O. V., Osipova A. A., Samoilova A. V., Matveeva V. A., Gunin A. G. Hormonal status of women with endometrial hyperplastic processes. Reproduction Issues, 2006, 12, 3, 31-36
• TRANSLATION FROM ENGLISH: Heffner L. Human Reproduction at a Glance. Blackwell, 2001. Russian edition: Heffner L. The reproductive system in norm and pathology , Moscow, GEOTAR, 2003, 128 pp.