Nervous plate ( medullary plate , lat. Lamina neuralis ) is the primordium of the central nervous system in embryos of chordates , including humans . It is formed from the ectoderm under the stimulating influence of chordomesoderm [1] .
At the stage of formation of the neural plate, the embryo consists of three layers of cells: the ectoderm (from which the skin and nerve tissue are formed), the mesoderm (future muscles and bones) and the endoderm (digestive tract and respiratory tract). The precursor cells of the nervous tissue of the neural plate are neuroepithelial cells . If BMP-4 affects the cells, they develop as skin cells; otherwise, they develop into nerve cells [2] .
In the process of development, the neural plate forms a fold, which develops into a cylindrical neural tube ; this process is called primary neurulation .
Notes
- ↑ Neural plate - an article from the Great Soviet Encyclopedia .
- ↑ Paul A. Wilson, Giorgio Lagna, Atsushi Suzuki and Ali Hemmati-Brivanlou. Concentration-dependent patterning of the Xenopus ectoderm by BMP4 and its signal transducer Smad1. Development: The Company of Biologists Limited 124, Great Britain. 1997. pg 3177-3184