Dimethylglycine ( DMG ) is a derivative of the amino acid glycine with the structural formula (CH 3 ) 2 NCH 2 COOH. It can be found in legumes and liver. Can be obtained by removing one of its methyl groups from trimethylglycine . In addition, it is a byproduct of choline metabolism.
| Dimethylglycine | |
|---|---|
 | |
 | |
| Are common | |
| Systematic name | N , N- Dimethylglycine, 2- (dimethylamino) acetic acid |
| Chem. formula | C₄H₉NO₂ |
| Physical properties | |
| Molar mass | 103.12 g / mol |
| Classification | |
| Reg. CAS number | 1118-68-9 |
| PubChem | |
| Reg. EINECS number | |
| Smiles | |
| Inchi | |
| RTECS | |
| Chebi | and |
| ChemSpider | |
When DMH was first obtained, it was referred to vitamins as vitamin B 16 , but, unlike the true B vitamins , lack of DMH in the diet does not lead to any unhealthy consequences and therefore it does not meet the definition of the term vitamin . In modern conditions, dimethylglycine is defined as a food product and can be used without a doctor's prescription.
Application
Dimethylglycine can be used as a drug to enhance athletic capabilities, an immunostimulant , epilepsy, or mitochondrial disease . [1] [2] Published studies on this topic showed that there is practically no difference between the treatment of DMH and placebo in the spectrum of autism diseases. [3] [4]
Links
- ↑ Dimethylglycine . About Herbs, Botanicals & Other Products . Memorial Sloan Kettering Cancer Center (December 8, 2009). Archived on September 7, 2012.
- ↑ Chinnery P., Majamaa K., Turnbull D., Thorburn D. Treatment of mitochondrial diseases (neopr.) // Cochrane (organization) . - 2006. - No. 1 . - S. CD004426 . - DOI : 10.1002 / 14651858.CD004426.pub2 . - PMID 16437486 .
- ↑ Bolman WM, Richmond JA Double-blind, placebo-controlled, cross-sectional pilot study of the effects of small doses of dimethylglycine in patients with autism (Russian) // Journal of Autism and Developmental Disorders : magazine. - 1999. - June ( t. 29 , No. 3 ). - S. 191-194 . - PMID 10425581 .
- ↑ Kern JK, Miller VS, Cauller PL, Kendall PR, Mehta PJ, Dodd M. The efficacy of N, N-dimethylglycine in the treatment of autism and mental development disorders (Russian) // Journal of Child Neurology : magazine. - 2001. - March ( t. 16 , No. 3 ). - S. 169-173 . - PMID 11305684 . Archived July 10, 2012. Archived July 10, 2012.