Aurovertin - a group of antibiotics , according to the chemical structure belonging to polyene pyrone . A powerful inhibitor of oxidative phosphorylation in mitochondria .
| Aurovertin B | |
|---|---|
 | |
| Chemical compound | |
| Gross formula | C 25 H 32 O 8 |
| CAS | |
| Pubchem | |
Getting
The source of aurovertin E and aurovertin B is mycelial tissue and the culture fluid of basidiomycete Albatrellus confluens .
Application
First proposed to use it to study the functions of mitochondria Henry Lardy (Henry Lardy).
Links
- J Antibiot (Tokyo). 2005 Jun; 58 (6): 412-5 16156519 Aurovertin E, a new polyene pyrone from the basidiomycete Albatrellus confluens. Fei Wang, Du-Qiang Luo, Ji-Kai Liu
- Molecular Pharmacology, Vol 11, 166-173, 1975 Antibiotics as Tools for Metabolic Studies XVIII. Inhibition of Sodium- and Potassium-Dependent Adenosine Triphosphatase JOHN B. SUSA 1 and HENRY A. LARDY 1