Oleamide ( octadec-9-enamide ) is an oleic acid amide .
| Oleamide | |
|---|---|
 | |
 | |
| General | |
| Systematic name | octadec-9-enamide |
| Traditional names | oleamide |
| Chem. formula | C₁₈H₃₅NO |
| Rat formula | C 18 H 35 NO |
| Physical properties | |
| condition | solid |
| Molar mass | 281.4766 g / mol |
| Thermal properties | |
| T. melt. | + 75-76 C |
| Classification | |
| Reg. CAS number | |
| PubChem | |
| Reg. EINECS number | |
| Smiles | |
| Inchi | |
| Chebi | |
| ChemSpider | |
Content
- 1 Biological activity
- 2 Application
- 3 notes
- 4 Literature
Biological Activity
The cis isomer of oleamide plays a role in falling asleep. It was found that cis- oleamide accumulates in the cerebrospinal fluid of cats and rats deprived of sleep. The mechanism of its action is associated with the modulation of 5-HT , GABA and CB 1 receptors. It is an endogenous selective agonist of cannabioid receptors CB1 [1] .
Application
Oleamide is used as an additive in the production of polymers . Diffusing to the surface of the product, oleamide forms an ultrathin layer that performs the function of a lubricant .
Notes
Literature
- Charles A. Harper, Edward M. Petrie. Plastics materials and processes: a concise encyclopedia . - John Wiley and Sons, 2003 .-- S. 511-512. - 974 s. - ISBN 0471456039 .
- Wallace B Mendelson1 and Anthony S Basile. The Hypnotic Actions of the Fatty Acid Amide, Oleamide // Neuropsychopharmacology. - 2001. - T. 25 , No. S5 . - S. S36-S39 .
- EMCDDA. Understanding the 'Spice' phenomenon . - Lisbon: EMCDDA, 2009 .-- 37 p. - ISBN 9789291684113 . Archived on May 29, 2010. Archived February 2, 2013.