Dansylamide ( Eng. Dansyl amide ) is a fluorescent chemical compound. It is used in biochemistry and chemistry for fluorescent labeling of substances, for example amino acids [2] or nucleotides [3] like dansyl chloride . Initially, the dance labeling method was developed in 1963 for labeling peptides.
| Dansilamide | |
|---|---|
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| General | |
| Systematic name | 5- (dimethylamino) naphthalene-1-sulfonamide |
| Chem. formula | C 12 H 14 N 2 O 2 S |
| Physical properties | |
| condition | liquid |
| Molar mass | 250.317 g / mol |
| Thermal properties | |
| T. melt. | |
| Classification | |
| Reg. CAS number | |
| PubChem | |
| Reg. EINECS number | |
| Smiles | |
| Inchi | |
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Notes
- ↑ Bradley J. , Williams A. , Andrew SID Lang Jean-Claude Bradley Open Melting Point Dataset // Figshare - 2014.- doi: 10.6084 / M9.FIGSHARE.1031637.V2
- ↑ Tapuhi Y., Schmidt DE, Lindner W., Karger BL Dansylation of amino acids for high-performance liquid chromatography analysis (Eng.) // Anal. Biochem. : journal. - 1981. - July ( vol. 115 , no. 1 ). - P. 123-129 . - PMID 7304940 .
- ↑ Misra A., Tripathi S., Misra K. Fluorescent labelling of ribonucleosides at 2'-terminus; comparative fluorescence studies // Nucleic Acids Symp. Ser. : journal. - 2000. - No. 44 . - P. 291-292 . - PMID 12903383 .
Links
- Gray, WR and Hartley, BS (1963) A fluorescent end group reagent for peptides and proteins. Biochem. J. 89, 59P.