Toxascarosis (toxascarosis) is a helminthiasis from the group of nematodoses , characterized by dispensary disorders and allergic manifestations.
Content
Etiology
The causative agent is the nematode Toxascaris leonina. The length of the male is 40-60 mm, the females - 55-120 mm.
Helminth parasitizes dogs and other carnivores, as well as humans.
Human infection occurs through the use of food and water contaminated by faeces of animals containing parasite eggs.
Pathogenesis
From the eggs swallowed by humans, the larvae emerge, which after migration for several days in the intestinal wall return to the intestinal lumen, where they turn into imago ; larvae from the intestine can migrate into the internal organs and tissues hematogenously and encapsulate there.
In humans, toxascarosis caused by migratory larvae and toxascarosis caused by sexually mature helminths are distinguished.
Toxascarosis caused by larvae is characterized by the appearance of eosinophilic infiltrates in the lungs, granulomas in various organs and tissues, eosinophilia , and leukocytosis. The diagnosis is established according to serological reactions of indirect hemaglutination. The treatment is carried out with thiabendazole at 25 mg / kg per day in cycles of 3-7 days.
The clinical picture of toxascarosis caused by sexually mature forms is manifested by nausea, vomiting, abdominal pain, and eosinophilia. There are isolated observations when parasites were found in abscesses of the subcutaneous tissue. The diagnosis is confirmed by the detection of pathogen eggs in the feces of the patient. For treatment, piperazine adipate is used, as in ascariasis .
The prognosis is usually favorable.
Literature
- Big Medical Encyclopedia, vol. 25, p. 103.
See also
- Invasion