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Amiton

Amiton (tetram, inferno, metramak, viji) is a nerve agent, a toxic warfare agent . Its lethal dose is approximately 10 times the lethal dose of VX : LD 50 in mice is 0.235 mg / kg (subcutaneously) and 0.5 mg / kg (intraperitoneally), i.e., toxicity is comparable to sarin .

Amiton
VG-2D-skeletal.png
Amiton
Are common
Systematic
name
S-diethylaminoethyl, bis-O-ethyl ester of thiophosphoric acid
AbbreviationsVG, EA 1508
Chem. formulaC 10 H 24 NO 3 PS
Physical properties
conditioncolorless liquid
Molar mass198.176 g / mol
Thermal properties
T. bale.300 ° C
Classification
Reg. CAS number78-53-5
PubChem
Smiles
Inchi
ChemSpider
Security
LD 500.5 mg / kg
Toxicity
NFPA 704.svg
0
four
0
Hazard TT.svg

In 1952, several researchers simultaneously worked on the study of the class of complex organophosphates. Dr. Lars-Eric Tammelin worked on this topic for the Swedish National Defense Research Institute, and for obvious reasons his work was not widely published. J. F. Newman and Ranajit Ghosh, chemists at the Imperial Chemical Industries field protection research lab, also worked in this area and found that organophosphates are highly effective as pesticides .

In 1954, one of the substances of this class, ICI launched onto the market under the trade name Amiton, but the product was immediately withdrawn due to its high toxicity. The toxicity of Amiton did not go unnoticed by the military, and samples of the substances were sent to the Porton Down military research park. Upon completion of the study, a number of substances of this class constituted a new group of nerve agents - V-agents , and Amiton received the designation VG.

Peaceful application

Amiton is a good insecticide and acaricide , but due to its high toxicity to warm-blooded animals, it is not widely used in agriculture.

Literature

  • V.N. Aleksandrov , V.I. Emelyanov Poisoning substances - Moscow, Military Publishing House - 1990.

Links

  • Amiton at Pubmed Compound
Source - https://ru.wikipedia.org/w/index.php?title=Amiton&oldid=95286123


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Clever Geek | 2019