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Genetic analysis

Genetic analysis - the study of the genotype of individual individuals, groups of individuals and the genetic structure of populations, including lines, strains, varieties, breeds, etc. [1]

Content

  • 1 Basic concepts
  • 2 Tasks of genetic analysis
  • 3 study levels
  • 4 notes
  • 5 Links

Key Concepts

The objects of genetic analysis are prokaryotes and eukaryotes. The study is carried out by genetic modeling. The following genetic analysis methods are used.

  • Hybrid method
  • Genealogical
  • Twin methods
  • Somatic Cell Hybridization Methods
  • Nucleic Acid Hybridization
  • Tissue transplantation
  • Analysis of transgenic and chimeric organisms
  • Cytogenetic
  • Biochemical
  • Embryological
  • Population
  • Molecular
  • Statistical and mathematical methods.

The choice of genetic analysis methods for objects of different levels of organization and depending on the tasks and levels of research.

Genetic Analysis Tasks

  1. identification of traits and genes to be examined
  2. gene localization, genetic mapping
  3. identification of gene function, establishing the nature of the mutation
  4. determination of what is regulated by the sign.

Study Levels

  • molecular. At this level, nucleic acid is examined. Sequencing, biochemical methods are used (determination of the size of nanocrystals, melting point, communication with proteins)
  • subcellular. Organelles with their own NK, as well as chromosomes, are being studied. Cytogenetic methods: microscopy, staining.
  • cellular. “Ontogenetic” methods, that is, a study of how genetic information is realized at different levels at different stages of cell life.
  • organismic. Mutation and recombination analysis, hybridological (genealogical), twin methods are used.
  • population. Population analysis and statistical methods are used.

Notes

  1. ↑ GENETIC ANALYSIS (neopr.) (Inaccessible link) . Date of treatment November 29, 2009. Archived April 14, 2010.

Links

Department of Genetics, Faculty of Biology, Moscow State University named after M.V. Lomonosov

Source - https://ru.wikipedia.org/w/index.php?title= Genetic_analysis&oldid = 101239437


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Clever Geek | 2019