11-beta-hydroxysteroid dehydrogenase, type 2 is a human enzyme involved in steroidogenesis and encoded by the HSD11B2 gene on the 16th chromosome . It is one of two isoforms of the 11β-HSD enzyme.
| 11-beta-hydroxysteroid dehydrogenase type 2 | |||||||||||||
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| Identifiers | |||||||||||||
| , AME, AME1, HSD11K, HSD2, SDR9C3, hydroxysteroid (11-beta) dehydrogenase 2, hydroxysteroid 11-beta dehydrogenase 2 | |||||||||||||
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| Kinds | Person | Mouse | |||||||||||
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| Uniprot | |||||||||||||
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| View / Edit (Man) | View / Edit (Mouse) | ||||||||||||
Medical Importance
Mutations in the HSD11B2 gene cause 11-beta-ketoreductase deficiency or the “ syndrome of apparent excess mineralocorticoids ” ( OMIM 218030 ).