Chromosomal ideogram of human chromosome 15
The 15th human chromosome is one of 23 human chromosomes . The chromosome contains more than 102 million base pairs [1] , which makes up from 3 to 3.5% of the total DNA material of a human cell . Data on the number of genes on the chromosome as a whole differ due to different approaches to counting. It probably contains from 700 to 900 genes .
Genes
Listed below are some genes located on chromosome 15 .
Shoulder p
- RNR3 - ribosomal RNA 3.
Shoulder q
- ANPEP - alanine amino peptidase ;
- AQP9 - aquaporins group protein, channel with a wide spectrum of permeability;
- CAPN3 - calpain 3;
- CYP11A1 - “Cholesterol side chain enzyme”, P450scc (scc: English side chain cleavage)
- CYP19A1 - aromatase;
- FAH - fumarylacetoacetate hydrolase, or fumarylacetoacetase;
- FUR - FURIN;
- FBN1 - fibrillin 1;
- HEXA , α-subunit of hexosaminidase A;
- ITGA11 is a glycoprotein from the integrin superfamily (alpha-11);
- IVD - isovaleryl-CoA-dehydrogenase;
- MCPH4 - gene 4 associated with primary autosomal recessive microcephaly ;
- OCA2 - gene associated with cutaneous ocular albinism, or protein P;
- RAD51 is a homolog of RAD51 ( S. cerevisiae ), or a homolog of RecA ( E. coli );
- STRC - stereocillin;
- TSP1 - thrombospondin-1;
- UBE3A - ubiquitin-protein ligase E3A;
- PML - protein of promyelocytic leukemia ;
- SLC24A5 is a member of the 5 family of solute carriers 24.
Notes
- ↑ Human chromosome 15 map view (English) . Vertebrate Genome Annotation (VEGA) database . The Wellcome Trust Sanger Institute . - Chromosome map and its main parameters: size, number of genes, etc. Archived April 10, 2012. (Checked October 12, 2009)