Chloride channel Kb Expressed in the kidneys . The closest in structure to the chloride channel Ka . Mutations of the CLCNKB gene lead to hereditary impairment of renal function, Bartter’s syndrome .
| Chloride Channel Kb | |||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||||||
| Symbol | ; CLCKB; ClC-K2; MGC24087; hClC-Kb | ||||||||||||
| External IDs | GeneCards : | ||||||||||||
| |||||||||||||
| RNA expression profile | |||||||||||||
 | |||||||||||||
 | |||||||||||||
| Orthologists | |||||||||||||
| View | Person | Mouse | |||||||||||
| Entrez | |||||||||||||
| Ensembl | |||||||||||||
| Uniprot | |||||||||||||
| RefSeq (mRNA) | |||||||||||||
| RefSeq (protein) | |||||||||||||
| Locus (UCSC) | |||||||||||||
| Search PubMed | |||||||||||||
Links
- Kieferle S., Fong P., Bens M., et al. Two highly homologous members of the ClC chloride channel family in both rat and human kidney. (Eng.) // Proceedings of the National Academy of Sciences of the United States of America : journal. - 1994. - Vol. 91 , no. 15 . - P. 6943-6947 . - DOI : 10.1073 / pnas.91.15.6943 . - PMID 8041726 .
- Takeuchi Y., Uchida S., Marumo F., Sasaki S. Cloning, tissue distribution, and intrarenal localization of ClC chloride channels in human kidney. (Eng.) // Kidney Int. : journal. - 1996. - Vol. 48 , no. 5 . - P. 1497-1503 . - DOI : 10.1038 / ki.1995.439 . - PMID 8544406 .
- Saito-Ohara F., Uchida S., Takeuchi Y., et al. Assignment of the genes encoding the human chloride channels, CLCNKA and CLCNKB, to 1p36 and of CLCN3 to 4q32-q33 by in situ hybridization. (English) // Genomics : journal. - Academic Press , 1997. - Vol. 36 , no. 2 . - P. 372-374 . - DOI : 10.1006 / geno.1996.0479 . - PMID 8812470 .
- Simon DB, Bindra RS, Mansfield TA, et al. Mutations in the chloride channel gene, CLCNKB, cause Bartter's syndrome type III. (Eng.) // Nat. Genet. : journal. - 1997. - Vol. 17 , no. 2 . - P. 171-178 . - DOI : 10.1038 / ng1097-171 . - PMID 9326936 .