Endothelial nitric oxide synthase (eNOS) is one of the human NO synthases encoded by the NOS3 gene on the 7th chromosome . The eNOS enzyme and the NOS3 gene were described in 1992-1993. [1] [2] [3]
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By synthesizing NO in blood vessels, NOS3 affects their functioning.
Notes
- ↑ Janssens, SP; Shimouchi, A .; Quertermous, T .; Bloch, DB; Bloch, KD: Cloning and expression of a cDNA encoding human endothelium-derived relaxing factor / nitric oxide synthase. J. Biol. Chem. 267: 14519-14522, 1992. PMID 1378832
- ↑ Marsden, PA; Schappert, KT; Chen, HS; Flowers, M .; Sundell, CL; Wilcox, JN; Lamas, S .; Michel, T.: Molecular cloning and characterization of human endothelial nitric oxide synthase. FEBS Lett. 307: 287-293, 1992. PMID 1379542
- ↑ Marsden, PA; Heng, HHQ; Scherer, SW; Stewart, RJ; Hall, AV; Shi, X.-M .; Tsui, L.-C .; Schappert, KT: Structure and chromosomal localization of the human constitutive endothelial nitric oxide synthase gene. J. Biol. Chem. 268: 17478-17488, 1993. PMID 7688726