Hygrin - alkaloid , a derivative of pyrrolidine .
| Hygrin | |
|---|---|
 | |
| Are common | |
| Systematic name | ( R ) -1- (1-methylpyrrolidin-2-yl) -propan-2-one |
| Chem. formula | C₈H₁₅NO |
| Physical properties | |
| condition | liquid |
| Molar mass | 141.2108 g / mol |
| Density | 0,935 g / cm³ |
| Thermal properties | |
| T. Kip. | 193-195 ° C |
| Chemical properties | |
| Rotation [α] D | 1.30 ° |
| Classification | |
| Reg. CAS number | |
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| CHEBI | |
| Chemspider | |
History
Hygrin was first discovered in the leaves of a variety of coca in 1862. In 1939 it was isolated from the gammadol bindweed ( lat. Convolvulus hammadae ).
Properties
Colorless volatile liquid, strong tertiary base. In living organisms it is synthesized from ornithine or arginine . The pyrrolidine ring occurs during the intramolecular reaction of the formation of the Schiff base , the acetyl group is derived from acetyl coenzyme A.
Literature
- Orekhov A.P. Chemistry of alkaloids. - Izd.2. - Moscow : USSR Academy of Sciences, 1955. - 859 p.
- Paul M Dewick. Medicinal Natural Products. A Biosynthetic Approach. Second Edition. - Wiley, 2002. - 515 s. - ISBN 0471496405 .