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Toll-like receptor 9

Toll-like receptor 9 (TLR9, CD289) is a membrane protein that is part of the group of toll-like receptors that ensure the functioning of innate immunity . The gene product of TLR9 [1] . TLR9 is expressed on cells of the immune system, including dendritic cells , macrophages , natural killers and other antigen-presenting cells [1] . Recognizes CpG sites on a DNA molecule that are relatively rare (~ 1%) in vertebrate DNA compared to bacterial or viral DNA. It is an intracellular protein localized in endosomes .

Toll-like receptor 9
Identifiers
, CD289, toll like receptor 9
External IDs
Gene ontology
Functions

Cell component

Biological process

Sources: Amigo / QuickGO
Orthologists
KindsPersonMouse
Entrez
Ensembl
Uniprot
RefSeq (mRNA)

RefSeq (protein)

Locus (UCSC)
PubMed Search
Wikidata
View / Edit (Man)View / Edit (Mouse)

Literature

  • Randhawa AK, Hawn TR Toll-like receptors: their roles in bacterial recognition and respiratory infections (Eng.) // Expert Rev Anti Infect Ther: journal. - 2008 .-- August ( vol. 6 , no. 4 ). - P. 479-495 . - DOI : 10.1586 / 14787210.6.4.479 . - PMID 18662115 .

Notes

  1. ↑ 1 2 Du X., Poltorak A., Wei Y., Beutler B. Three novel mammalian toll-like receptors: gene structure, expression, and evolution (English) // European Cytokine Network: journal. - 2000 .-- September ( vol. 11 , no. 3 ). - P. 362-371 . - PMID 11022119 .

Links

  • Find a CpG motif, or Fine work of a toll-like receptor 9 (neopr.) . Biomolecule. Date of treatment March 22, 2019.
Source - https://ru.wikipedia.org/w/index.php?title=Toll-like_receptor_9&oldid=100894995


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Clever Geek | 2019