Camphonium ( Camphonium ). ganglion blocker . N- (-Dimethylaminopropyl) -camphidine diiodomethylate.
| Camphony | |
|---|---|
| Chemical compound | |
| Gross formula | C 17 H 36 I 2 N 2 |
| CAS | |
| Pubchem | |
A similar disulfomethylate is known under the names: Camphidonium, Methocamphonii methylsulfas, Ostensin, Ostensol, Trimethidinium methosulfate.
General Information
Crystalline powder, white with a slightly yellowish tint. Soluble in water, slightly soluble in alcohol.
Refers to bis-quaternary ammonium compounds.
Indications for use are the same as for other ganglion blockers of this group.
Assign under the skin, into the muscles and inside, and for controlled hypotension - into the vein.
With obliterating endarteritis , hypertensive disease of the I-II stage, gastric ulcer, it is prescribed orally, starting with a dose of 0.005 g 1-2 times a day; with good tolerance, the dose is gradually increased to 0.01-0.05-0.1 g 1-2 times a day. Treatment is carried out in courses (for 2-3 weeks).
Parenterally administered, starting with 0.5-1 ml of a 1% solution (0.005-0.01); with good tolerance, a single dose can be increased to 0.05 g (5 ml of a 1% solution); injections are performed 1-2-3 times a day.
With hypertension, camphonium can be used topically with other antihypertensive drugs.
For controlled hypotension, 0.25-0.5-1 ml of a 1% solution is injected into a vein for 1-1.5 minutes. With prolonged operations, you can repeat the injection after 1-1.5 hours.
Contraindications
Possible side effects and contraindications are the same as for the entire group of ganglion blocking drugs.
Release form
- 0.01 and 0.05 g tablets
- 1% solution in ampoules of 1 ml.