Desoxypeganine hydrochloride ( Desoxypeganini hydrochloridum ). 2,3-trimethylene-3,4-dihydroquinazoline hydrochloride.
| Deoxypeganine hydrochloride | |
|---|---|
| Chemical compound | |
| Gross formula | C 11 H 13 ClN 2 |
| Cas | |
| PubChem | |
| Other names | |
| Deoxypeganine | |
Alkaloid hydrochloride from common harmala grass (Peganum harmala L.)
It has a reversible anticholinesterase effect.
Content
Indications
Assign to patients with lesions of the peripheral nervous system ( mononeuritis , neuritis , polyneuritis ); with myasthenia gravis and myopathy-like conditions, with hemiplegia , hemiparesis , lesions of the anterior horns of the spinal cord.
Dosage and administration
Take orally or injected under the skin. Inside appoint adults in a single dose of 0.05-0.1 g 3 times a day (daily dose of 0.15-0.3 g). Children aged 12-14 years - 0.01-0.025 g per reception, up to 0.1 g per day; over 14 years old - at 0.025-0.05 g per dose, daily dose 0.2 g.
A single dose under the skin for adults 1-2 ml of 1% solution (0.01-0.02 g). The daily dose of 0.05-0.1 g.
The duration of treatment is 2-4-6 weeks.
Contraindications
Possible side effects and contraindications are the same as when using other anticholinesterase drugs.
Physical Properties
Fine crystalline powder, white or white with a slightly yellowish tint. Soluble in water, little in alcohol.
Release form
- 0.05 and 0.1 g tablets
- 1% solution in ampoules of 1 and 2 ml (10 and 20 mg).