Immunopharmacology

As a branch of pharmacology arose more than 30 years ago. Since 1978, in the UK, the international journal Immunopharmacology and Immunotoxicology [2] , Immunopharmacology and Immunotoxicology ^{[1] has been} published in English. In 1984, the fundamental “Guidelines for Immunopharmacology” was published in English and translated into Russian; in 1989, the second edition of the guidelines was published (published in Russian in 1998) ^[2] .

Immunopharmacology will study the pharmacological aspects associated with the body's immune response, both in physiological and pathological processes. As you know, the mechanisms of the body's immune response are being studied - immunology . Immunopharmacology is an interdisciplinary discipline at the intersection of immunology and pharmacology ^[3] . Immunopharmacology is engaged in research:

• the effect of drugs on inflammation and the immune response ^[2] ,
• immunotoxicity of drugs ^{[4] [5] [6]} ,
• preclinical and clinical studies of the regulatory effects of pharmacological agents on immunocompetent cells ,
• pharmacological mechanisms and effects that have immunomodulators ( immunosuppressants , immunostimulants ), cytokines , mediators and other biologically active substances.

Recent achievements in immunopharmacology: the study of the processes of stimulus conjugation and activation in the cell, especially those associated with the exchange of polyphosphosphoinositides and the formation of secondary messengers ^[2] , the creation of new immunomodulating agents used to treat primary immunodeficiency , cancer, allergies , arthritis (and other conditions associated with the implementation of hypersensitivity of types I-V, sepsis, damage to various organs, systems, cells, enzymes, molecules by ionizing radiation, prevention and treatment Ia postintoksikatsionnyh immunodeficient states and other secondary immunodeficiencies ^[5] , which lead to infectious complications and diseases ^[7] , hypersensitivity reactions, autoimmune disease ^[5] .