Tiaprid

Tiapride is an atypical antipsychotic from the group of substituted benzamides, first synthesized in 1972 in France, after clinical trials it was approved for medical use in the USSR.

In structure and pharmacological properties, tiapride is close to sulpiride . It has an antidopaminergic effect.

It is used for hyperkinetic and dyskinetic disorders (chorea, nervous tics, senile psychomotor disturbances, trembling, etc.), headaches of neurogenic origin, reactive disorders of behavior, as well as psychomotor agitation and autonomic disorders in case of acute alcohol psychosis and withdrawal symptoms in patients alcoholism and drug addiction.

Assign inside and in the form of injections. Inside, it is taken for movement disorders of 0.3-0.6 g per day (in 2-3 doses), for reactive conditions with psychomotor agitation - 0.6-1.2 g per day, for alcoholism, headaches - 0.2-0.4 g per day. After the therapeutic effect is achieved, the dose is reduced to 0.1-0.2 g per day.

Children aged 7 to 12 years with psychomotor imbalance or nerve tics are prescribed inside 0.05 g (1/2 tablet) 1-2 times a day.

For elderly patients, the drug is prescribed at a dose of 0.2-0.3 g per day, if necessary, the dose is slightly increased.

Intramuscularly, tiapride is administered to adults at 0.4 g (400 mg) per day.

If necessary, tiapride can be used in combination with antipsychotics , tranquilizers , antidepressants , analgesics and other neurotropic drugs.

Typically, tiapride is well tolerated. In some cases, drowsiness, seizures such as dyskinesia (convulsive movements of the eyeball, jaw compression) are observed. As a rule, these phenomena pass independently. If necessary, antiparkinsonian drugs are prescribed. In rare cases, amenorrhea , galactorrhea develop.

Storage: List B.

• Organics , more than 50% of Russian production ^[1]