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Pufemid

Pufemid (Puphemidum). 3- (p-Isopropoxyphenyl) succinimide

Pufemid
Chemical compound
Gross formulaC 13 H 15 NO 3
Cas
PubChem

Content

General Information

Like ethosuximide , it is a derivative of succinic acid imide . In structure, it differs from ethosuximide in that instead of methyl and ethyl at the nitrogen atom in position 3 it contains a para-substituted phenyl radical.

Like other drugs of this group ( succinimides ) it has anticonvulsant activity. It is used for epilepsy type petit mal, as well as for temporal lobe epilepsy.

Take orally before meals. Dose for adults - starting from 0.25 g 3 times a day; with insufficient effect, the dose is increased to 1.5 g per day. Children under the age of 7 are prescribed 0.125 g, older than 7 years - 0.25 g 3 times a day.

Pufemid can be used in combination with other antiepileptic drugs.

Possible side effects are nausea, insomnia. With nausea, it is recommended to take the drug 1-1.5 hours after eating, in case of sleep disturbance - no later than 3-4 hours before sleep.

Contraindications

The drug is contraindicated in acute diseases of the liver and kidneys, diseases of the hematopoietic system, with hyperkinesis, severe atherosclerosis.

Physical Properties

White powder with a slightly yellowish tint. It is practically insoluble in water. Soluble in alcohol.

Release form

Release form: tablets of 0.25 g in a package of 50 pieces.


Source - https://ru.wikipedia.org/w/index.php?title=Pufemid&oldid=83793839


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