Roderick MacKinnon [1] ( born Roderick MacKinnon ; born February 19, 1956 , , Massachusetts , USA ) is an American biochemist and crystallographer , Nobel Prize winner in chemistry for ion channel research.
| Roderick McKinnon | |
|---|---|
| Roderick mackinnon | |
 | |
| Date of Birth | February 19, 1956 (63 years old) |
| Place of Birth | , Massachusetts , USA |
| A country |  USA |
| Scientific field | biochemistry |
| Place of work | |
| Alma mater | Brandeis University |
| Known as | ion channel researcher |
| Awards and prizes |  Nobel Prize in Chemistry ( 2003 ) |
Member of the US National Academy of Sciences (2000) [2] .
Content
Biography
Roderick McKinnon was born in Burlington ( Massachusetts , USA ). He initially enrolled at the , but a year later he transferred to Brandeis University for an in-depth study of science, where he studied calcium transport through cell membranes in the laboratory of Christopher Miller. In 1978, McKinnon received a bachelor's degree in biochemistry from Brandyce and enrolled at Tuft University Medical School. In 1982, he received a medical degree, but was dissatisfied with the work of the doctor. In 1986, McKinnon returned to Brandeis University to Miller's laboratory. In 1989, he became an assistant professor at Harvard University , where he began research on the interaction of the potassium channel with a specific toxin from scorpion venom. In 1989, he received a professor and laboratory of molecular neurobiology and biophysics at Rockefeller University , where he began work on the structure of the potassium channel due to the special importance of potassium channels in the nervous system and heart.
In 1998, McKinnon and colleagues were able to obtain the three-dimensional molecular structure of the bacterial potassium channel using crystallography and revealed the channel selectivity, namely, why the channel passes only potassium ions, and smaller sodium ions do not pass. Protein crystallography was based on the CHESS synchrotron radiation sources at Cornell University and the NSLS at Brookhaven National Laboratory .
Rewards
- 1995 -
- 1997 -
- 1998 -
- 1999 - Albert Lasker Prize for Basic Medical Research in collaboration with and , “For elucidating the functional and structural architecture of ion channel proteins, which govern the electrical potential of membranes throughout nature, thereby generating nerve impulses , and controlling muscle contraction, cardiac rhythm, and hormone secretion »
- 2000 - Rosenstyle Prize , "For his research into the molecular foundations of electrical signal generation in neurons and other types of cells"
- 2001 -
- 2003 - Louise Gross Horvitz Award
- 2003 - The Nobel Prize in Chemistry, together with Peter Agre , for the discovery of the three-dimensional molecular structure of the bacterial potassium channel and the disclosure of the nature of its selectivity.
- 2005 -
Notes
- ↑ McKinnon // Lomonosov - Manizer. - M .: Big Russian Encyclopedia, 2011. - P. 547. - ( Big Russian Encyclopedia : [in 35 vols.] / Ch. Ed. Yu. S. Osipov ; 2004—2017, vol. 18). - ISBN 978-5-85270-351-4 .
- ↑ Roderick MacKinnon