Interstitial lung diseases (ILD) are predominantly chronic diseases of the lung tissue, manifested by inflammation and impaired structure of the alveolar walls , endothelium of the pulmonary capillaries , perivasal and perilymphatic tissues (see alveolitis ). A characteristic symptom of interstitial lung disease is shortness of breath , which is a reflection of pulmonary failure [1] .
| Interstitial lung disease | |
|---|---|
 Pneumofibrosis as the outcome of interstitial lung tissue disease is “cell lung”. | |
| ICD-10 | J 84.9 |
| ICD-10-KM | |
| ICD-9 | 506.4 , 508.1 , 515 , 516.3 , 714.81 , 770.7 |
| Omim | |
| Diseasesdb | 31509 |
| eMedicine | ped / 1950 |
| Mesh | D017563 |
Most interstitial lung diseases lead to pneumofibrosis . Currently, the term "pneumofibrosis" is not synonymous with IFL, but is still used in this sense. To designate fibrosing ILI with an unclear root cause, the phrase "idiopathic pneumofibrosis" is used.
Classification
Interstitial lung diseases can be classified by etiological criteria.
- Inhalation of various substances from the surrounding atmosphere
- Inorganic substances
- Silicosis
- Asbestosis
- Berylliosis
- Organic matter
- Hypersensitive pneumonitis or exogenous allergic alveolitis
- Inorganic substances
- Drug response
- Antibiotics
- Chemotherapy drugs
- Antiarrhythmic drugs
- Systemic connective tissue diseases
- Scleroderma
- Systemic lupus erythematosus
- Rheumatoid arthritis
- Dermatomyositis
- Infections
- Atypical pneumonia
- Pneumocystis pneumonia
- Tuberculosis
- Idiopathic
- Sarcoidosis
- Idiopathic pneumofibrosis
- Histiocytosis X
- Alveolar Proteinosis
- Idiopathic interstitial alveolitis - acute interstitial alveolitis (acute interstitial pneumonia [2] , Hamman-Rich syndrome ), etc.
- Malignant tumors
- Lymphangitis carcinomatosis
- Associated IFL
- ILD associated with liver disease: chronic active hepatitis, primary biliary cirrhosis
- IPL associated with pulmonary vasculitis (Wegener's granulomatosis, lymphomatoid granulomatosis, systemic necrotizing vasculitis, hypersensitive vasculitis)
- IPL associated with the graft versus host reaction
Diagnostics
Diagnosis of ILD is based on the clinical picture, radiological studies (chest x-ray and CTEC ), pulmonary function tests and laboratory data. In case of doubt in the diagnosis, fibrobronchoscopy and / or lung biopsy is performed.
Notes
- ↑ Crystal, 1995 .
- ↑ Avnon et al., 2009 .
Literature
- Crystal R. J. Chapter 209. Interstitial lung disease // Internal Medicine. In 10 kn. = Hurrison's Principles of Internal Medicine, 11th Ed., 1987 / Ed. E. Braunwald et al. (Editor of the first edition T.R. Harrison). - M .: Medicine, 1995. - T. 6. - S. 111–126. - 416 p. - 50,000 copies. - ISBN 5-225-00623-X .
- Avnon LS, Pikovsky O., Sion-Vardy N., Almog Ya. Acute Interstitial Pneumonia – Hamman-Rich Syndrome: Clinical Characteristics and Diagnostic and Therapeutic Considerations (English) // Anesthesia & Analgesia. - 2009. - Iss. 108 (1) . - P. 232-237 . - ISSN 0003-2999 . - DOI : 10.1213 / ane.0b013e318188af7a . - PMID 19095855 . Archived August 1, 2013.