Haemophilus ducreyi (lat.) - a type of gram - negative bacteria of the genus hemophilus ( Haemophilus ), causing a sexually transmitted disease - mild chancre , widespread in developing countries around the world [1] [2] . The disease begins with pimpled formations on the genitals, which over time turn into ulcers with purulent plaque and uneven edges.
| Haemophilus ducreyi |
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| Scientific classification |
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| Grade: | Gamma proteobacteria |
| Order: | Pasteurellales Garrity et al. 2005 |
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| International scientific name |
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Haemophilus ducreyi
(Neveu-Lemaire 1921) Bergey et al. 1923 |
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Content
Morphology
A small (1.2-1.5 × 0.5 μm) rod - shaped bacterium with rounded edges. In smears from tissues and liquid cultures, they often form characteristic cell chains ( streptobacilli ). Fixed, forms a capsule .
Cultural Properties
Chemoorganeterotroph , facultative anaerobic . It does not grow on simple nutrient media; blood culture media ( blood agar , chocolate agar ) are used to cultivate the body; factor X is a necessary factor for growth on artificial nutrient media. On agarized culture media forms small, flat translucent (occasionally transparent) gray-yellow colonies. Under aerobic conditions, a high level of polymorphism of the shape of the colonies was noted, a pure culture may look like mixed [3]
Genome
The Haemophilus ducreyi genome of strain 35000HP is represented by a 1698955 bp ring double-stranded DNA molecule. and contains 1838 genes , of which 1717 encode proteins , the percentage of% G + C pairs is 84% [4] . Haemophilus ducreyi strain ATCC 27722 has a plasmid pNAD1, which is a 5568 bp ring double-stranded DNA molecule, contains 10 genes, of which 8 encode proteins [5] , the plasmid is responsible for NAD independence [6] .
